DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tum and Arhgap35

DIOPT Version :9

Sequence 1:NP_610912.2 Gene:tum / 36538 FlyBaseID:FBgn0086356 Length:625 Species:Drosophila melanogaster
Sequence 2:NP_766327.3 Gene:Arhgap35 / 232906 MGIID:1929494 Length:1499 Species:Mus musculus


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tumNP_610912.2 C1 319..367 CDD:237996
RhoGAP_MgcRacGAP 381..570 CDD:239847
Arhgap35NP_766327.3 Has GTPase activity, required for proper localization. /evidence=ECO:0000269|PubMed:11044403 1..266
RAS <158..250 CDD:214541
RhoGAP-FF1 261..340 CDD:406821
FF 371..422 CDD:128718
FF 431..483 CDD:128718
FF 486..539 CDD:128718
pseudoGTPaseD_p190RhoGAP-A 594..765 CDD:412066
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1124..1148
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1177..1207
Required for phospholipid binding and regulation of the substrate preference. /evidence=ECO:0000250|UniProtKB:Q9NRY4 1213..1236
RhoGAP_p190 1247..1431 CDD:239838
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1446..1499
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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