DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and rga-8

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001348821.1	Gene:	rga-8 / 180799	WormBaseID:	WBGene00021324	Length:	709	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	54/248 - (21%)
Similarity:	105/248 - (42%)	Gaps:	32/248 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   394 IPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGK--ATPHLGNTDIYVLCCCVKDF 456
            |..::..|.:.:...|:.|.|::|:|.:..:.|.::.....|:  |.....|.|.:.:...:|.:
Worm   305 ISGVLTKCCDFLRQNGMNERGIFRVSGNASKIKRIRAALDAGQFDADEKHYNNDPHAVASTLKAY 369

  Fly   457 LRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRI-AQCPVV 520
            ||.|.:||...|...|:..|: |.:.:.....:.:.:|::.:.:|..|.:|:.....: |:....
Worm   370 LRELPDPLTMDSLQSDWVEAI-NLEGEERFSAIDRCLKKMTRGHRQNLIYLMKFLCDLEAKREET 433

  Fly   521 LMPIDNISLIFGPTIVGYSTPDPDQHAI-YTEVFTQKQV----MKALLEL----PVSFWEQYIVI 576
            .|...|::::|.||:.|......:.|.: .||......|    ..||.:|    |..|......|
Worm   434 SMNASNLAIVFAPTMTGMIYDGMNTHGVKLTEFMISNGVRIFNFGALDKLDTSPPSGFTRAQSSI 498

  Fly   577 DP------TRTPATVIKRVPSNKNDLLSLYA------------TPFKGGTIKK 611
            .|      .:.|... .:.||...||::|::            :||.||::.:
Worm   499 SPRSFRPKEKAPPPP-SQTPSTSGDLINLHSGDDDDFSDDQSPSPFNGGSLTR 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	41/187 (22%)
rga-8	NP_001348821.1	BAR	109..297	CDD:386243
rga-8	NP_001348821.1	RhoGAP_nadrin	286..479	CDD:239851	37/174 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910