Protein Alignment tum and pac-1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_498877.4
• Gene: pac-1 / 176201
• WormBaseID: WBGene00015418
• Length: 1605
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 126/628 - (20%)
• Similarity: 214/628 - (34%)
• Gaps: 201/628 - (32%)

  Fly     7 ASFDDLRRCMQVLTDG--------TPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKM 63
            :||...|..::::|..        ..|.|.|.::.:.:...|.  |.|..::..:|||..:
 Worm   685 SSFSKQRHVVRIVTQNRSEHLIELNTESEMLSWISVLQSSSED--GIATGSSVDENELSTT---- 743

  Fly    64 GDLEGKLFHARRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERNLNN---------ETRDKL 119
                                   ..|..:|:.:.    :.||.:.:::.:         .|.:.|
 Worm   744 -----------------------GRHNNNAVSNS----SALLHNSQSIASLASSSCSTATTSEFL 781

  Fly   120 AFLHTLPSSRK----RKSLNAVRE-----------DKSYGDINSTGSLLSDLSITHSEDDFLDVR 169
            ...|||...::    :|....|.|           .||:|.:::|.|     |.|.:..:.|.:
 Worm   782 NSQHTLQQQQQQQTNQKHQQTVNELSAGIVSHLPTSKSFGGLSTTAS-----STTENAKNRLIM- 840

  Fly   170 TSKSWREHRPSLPKNQIPS-VGNKRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVG-- 231
                   ||.....:|:.| ..||:.........|.|.|..||..|        ...|:...|
 Worm   841 -------HRYIAKNSQLQSPTANKKMETDPSTVPSSSQTMATTSSS--------FHHHSSQAGPS 890

  Fly   232 ---QGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLT 293
               :..|  ..|...|.|:.|:...:::         |..:..|.|.|.:...|..:.|...| .
 Worm   891 RDIENGE--APTATATTPKSGRKWKKSK---------AAKQGSGGGSSGSSSGSQQQGAAGAP-Q 943

  Fly   294 PVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHID 358
            ||                                                :|:|..|||
 Worm   944 PV------------------------------------------------LGVRIADCP------ 954

  Fly   359 CRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSER 423
                                 ||...|.       :|.::..||..||..|:..||:||:..:..
 Worm   955 ---------------------TGSCEDH-------VPMIVQACVCVIETYGMDTVGIYRIPGNTA 991

  Fly   424 EYKALKEQFL-RGKATPHLGNT--------DIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQN 479
            ...||||... ||..:..|...        |:.|:...:|.|||.|.|||:....:..|.:|.:.
 Worm   992 AVNALKESLSNRGFDSVDLSKVESLDPRWRDVNVVSSLLKMFLRKLPEPLLTDKLYPFFIDANRI 1056

  Fly   480 PDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIAQ-CPVVLMPIDNISLIFGPTIVGYSTPDP 543
            .........|...:::||:.:.|||.|||:|...|.: ..|..|...|::|:|||:||..|  |.
 Worm  1057 STHHNRLHKLRNLLRKLPRPHYDTLRFLIVHLSEITKHSDVNKMECRNLALMFGPSIVRPS--DD 1119

  Fly   544 DQHAIYTEVFTQKQVMKALLELPVSFWEQYIVID---PTRTPA 583
            :...:.|.:..|.::::.|:...:..:::....:   |.:.||
 Worm  1120 NMATMVTHMSDQCKIIETLIHYNLWMFDESSTTEDAVPEQHPA 1162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	5/47 (11%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	56/198 (28%)
pac-1	NP_498877.4	PH_ARHGAP21-like	613..728	CDD:269955	8/44 (18%)
		PH	617..726	CDD:278594	7/40 (18%)
		RhoGAP_ARHGAP21	945..1146	CDD:239860	63/284 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910