DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and tag-325

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001309440.1	Gene:	tag-325 / 175636	WormBaseID:	WBGene00008006	Length:	840	Species:	Caenorhabditis elegans

Alignment Length:	431	Identity:	95/431 - (22%)
Similarity:	156/431 - (36%)	Gaps:	124/431 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 QHTVDVGQGAER------FCATTKVTI--PQDGQGV---IRAESTIESLPVI-AGNERIGDGLSS 277
            |...||.:..:|      .|.|.|..:  |.|.:.|   ...|..:..||.. :.|:.:.|..:.
Worm   462 QDNRDVQKKKQRKYIQLELCNTKKYLLRGPNDTEAVEWYKSLEEVVAKLPSPGSSNQPMIDVTNG 526

  Fly   278 TPRRSVLKEATAP------PLT--------PVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLR 328
            ..|......:|.|      |::        |::..|...|:.|.:..:.||       |::|.:
Worm   527 VARNPSYIGSTRPLSHALIPISRSMRRRDDPMSQSAIETVSTSVSTDEPRP-------SKETII- 583

  Fly   329 GDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTG----TPTTKTMTGYVTDFAPS 389
                   :|..||    .|.|.             ||..:.:.|    .|...:....:.....|
Worm   584 -------EKLRRF----FRTRP-------------TVESLKEKGIYKPEPVFGSTLSAICQHENS 624

  Fly   390 IAPMIPALIVHCVNEIEARGLTEVGLYRLS------------SSEREYKALKEQFLRGKATPHLG 442
            :.|....:|...   ||::||...|:||:|            :.:..||||            :.
Worm   625 LVPKFIRVITEV---IESKGLETDGIYRVSGNLSAVQKIRCQADQDNYKAL------------VS 674

  Fly   443 NTDIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFL 507
            ..||:||...:|.|.|.||:||.|.|..|::.:|:|.|:..|......:.:.:||..||:||..|
Worm   675 EEDIHVLTGALKLFFRELTDPLFPISLHKEYTSAMQMPNATTRFKKFEELLSRLPNENRETLKML 739

  Fly   508 ILHFQRIA-QCPVVLMPIDNISLIFGPTIV---------------------------GYSTPDPD 544
            :.|..|:| ......|...|::::||||:.                           ..:||...
Worm   740 LRHLNRVASHSSQNRMQQHNLAIVFGPTLFHNGDGAVNLATKNKKAGKKAKPSKKEETQATPVQS 804

  Fly   545 QHAIYTEVFTQKQVMKALLELPVSFWEQYIVIDPTRTPATV 585
            ...:...:..|.|:::.|||....|       |..:.|..:
Worm   805 NSHLAFSMIMQSQIVQYLLESANKF-------DILKAPVNI 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	9/47 (19%)
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	56/228 (25%)
tag-325	NP_001309440.1	WW	101..130	CDD:278809
		PH_ARHGAP9-like	391..509	CDD:270053	11/46 (24%)
		PH	407..508	CDD:278594	11/45 (24%)
		RhoGAP_ARHGAP27_15_12_9	611..825	CDD:239868	55/228 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910