Protein Alignment tum and F23H11.4

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_497289.1
• Gene: F23H11.4 / 175253
• WormBaseID: WBGene00017760
• Length: 1003
• Species: Caenorhabditis elegans
• Alignment Length: 596
• Identity: 111/596 - (18%)
• Similarity: 187/596 - (31%)
• Gaps: 197/596 - (33%)

  Fly   124 TLPSSRKRKSLNA-VREDKSYGDINSTGSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIP 187
            :|.||:|.|.|:. :|        |...|...|...|...:...|::....:|......|...|
 Worm   342 SLTSSKKEKRLHCRLR--------NMQLSFHDDEDSTEPSNGTFDIKGIYLFRHMASDTPYILI- 397

  Fly   188 SVGNKRS----------------------RLSTGLNG--------SMSGTT----PTTGKSRRSS 218
            .||.||:                      .|:.||..        ::.|.|    .|||:.:..|
 Worm   398 HVGEKRNVISFIPEDPPNLWMFFLSEAWLSLNYGLTSVLRDADELTICGITWIKHGTTGEWKICS 462

  Fly   219 VGI-GVEQH--TVDV-----GQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGL 275
            .|| |:..|  .||.     .:.:||..|.|...            ||:.|:        |||.|
 Worm   463 AGINGLTLHYMLVDAKDRIYNRNSERSDAGTSFM------------STVGSI--------IGDEL 507

  Fly   276 SSTPRRSVL---------------KEATAPPLTPVNAMAPHVVAESGTPLQH------RPLMRNH 319
            .....|.|:               :....|....::.:..::.:...:...|      ..|.|..
 Worm   508 VEVDLRKVMTMRERIDKSEFCPNARHKRGPFSITLHGVTLYIDSRDDSTTSHWYEAIEALLKRPA 572

  Fly   320 TFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVT 384
            |..:...|.|||
 Worm   573 TRLENLRLTGDN----------------------------------------------------- 584

  Fly   385 DFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLR---GKATPHLGNTDI 446
                     ||.::..|:..:.|.|:...|:||.:....|.|.:..:...   |....|..:..:
 Worm   585 ---------IPVIVDKCIRFVSAYGMKCEGIYRRNGKVTEAKTILTKLTEDPVGYYPVHENDETV 640

  Fly   447 YVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQL----PQANRDTLAFL 507
            |.:...::.|.|.|..||.|:|...|..:..    |::..|.|.....||    ...:|.||..|
 Worm   641 YAVADVLRQFFRKLDAPLFPSSSQADLFDLA----TESQSDELCARYAQLINTFELVHRSTLKKL 701

  Fly   508 ILHFQRIAQ-CPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSF-- 569
            |.|.:.::: .......::|::.:|..::  :.|...|: .:::|.:..:  :..|:.|...:
 Worm   702 IGHLKNVSEHAQENRASVENLAKVFAASL--FLTDAMDE-KVFSESYNHQ--INVLIHLTTGYDV 761

  Fly   570 ---------WEQYIVIDPTRTPATVIKRVP-----------SNK--NDLLSLYATPFKGGTIKKR 612
                     ..:.:|.|..:......|..|           .|:  |..:||.:.......|.||
 Worm   762 VFQISIEEELSRQMVNDAEKKSFNAKKPSPDFIVAIHVWEKENRPFNVKMSLASEEVCREAIAKR 826

  Fly   613 KFYGTPPASAH 623
            .|.| ||.|.:
 Worm   827 GFDG-PPDSPY 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	5/47 (11%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	39/207 (19%)
F23H11.4	NP_497289.1	RhoGAP_ARAP	571..759	CDD:239850	44/258 (17%)
		RA_ARAPs	790..882	CDD:340633	13/48 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910