Protein Alignment tum and spv-1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_495666.4
• Gene: spv-1 / 174278
• WormBaseID: WBGene00014051
• Length: 966
• Species: Caenorhabditis elegans
• Alignment Length: 676
• Identity: 126/676 - (18%)
• Similarity: 217/676 - (32%)
• Gaps: 257/676 - (38%)

  Fly    10 DDLRRCMQV-LTDGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSL------TKMGDLE 67
            |.:|..::| .|..|      :.|...|:.:||    :..|.|::.|..|..      |:....|
 Worm   299 DTVRNALKVEWTKAT------KSLHDCEESYEK----SKITLRMREEALKKARESCLRTESSPPE 353

  Fly    68 GKLFHARRIIDMEIKARRQAEHERDAMESKIMAVADLLRHER----------------------- 109
            .:....||.::.:.:|..:|..:::..|.:::::...||.:|
 Worm   354 REASRRRRDLEKKSRAVEEAMIKKEEAERQVVSITAELRKKRRDIDKTKESVVERLRELIFQCEQ 418

  Fly   110 -------------------------NLNNETRD------KLAFLHTLPSSRKRKSLNAVREDKSY 143
                                     .|:|.|||      .:|||.||| :|...|.:.||.|:|.
 Worm   419 TTKACTVHYFTSLAALWARLPGAFHELSNATRDYQPGTEYMAFLQTLP-TRAASSSSLVRSDRSI 482

  Fly   144 GDINSTGSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGLNGSMSGTT 208
            .:  ...|.....|:|                    ||.:|.|              |....|..
 Worm   483 DE--GVASCDGSSSLT--------------------SLRRNAI--------------NPDDEGAL 511

  Fly   209 PTTGKSRRSS-VGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIG 272
            |.|.:.:::| .|...:.|.:
 Worm   512 PDTKRHKKTSYAGRTFDNHEI-------------------------------------------- 532

  Fly   273 DGLSSTPRRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQK 337
                          :||       |.:.|:                    |:| ::...|..|..
 Worm   533 --------------STA-------AQSHHI--------------------QRT-VQPSKCSACDT 555

  Fly   338 RIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGY---VTDFAPSI--APM---- 393
            ......|  :|.||..:.|..|             .|..:.:.|.   :.|...||  .|:
 Worm   556 LSILYTV--QCIDCGGQWHKAC-------------FPRIQQVCGQAAKLVDRRTSIFGVPLKGLL 605

  Fly   394 ------IPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPH--LGNTDIYVLC 450
                  ||.:|...:::::.|||...|:||....:.:.:.:...|.|..:...  |.|.:...|.
 Worm   606 EHQNRHIPLIIEKSIDQLQRRGLRAKGIYRTCGVKSKIEEICNAFERSSSDDEVCLDNENPMNLA 670

  Fly   451 CCVKDFLRSLTEPLIPTSQWKDF---------ANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAF 506
            ..||.:||.|.|||:....:.||         |.|..:...:...:.|.:..::||..|.:||.|
 Worm   671 SVVKLYLRKLPEPLLTFELYDDFVRLGTECCSAQASGSNCEEERVEQLRQLARKLPVHNYETLKF 735

  Fly   507 LILHFQRIAQC-PVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPV--- 567
            ::||..|::.. .|.||...|:|.:..|:::..|....|    :|......|.....:|:.:
 Worm   736 IMLHLNRVSWFHEVNLMSTSNLSTVIAPSLIWMSPKRID----HTSAIMHTQYTNKAIEVMIRNS 796

  Fly   568 -------------SFWEQYIVIDPTR 580
                         ||:.:|.|.:|.:
 Worm   797 YHIFGMDRQADWQSFFSRYSVEEPPK 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	10/47 (21%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	53/231 (23%)
spv-1	NP_495666.4	FCH	195..278	CDD:214492
		C1	537..583	CDD:197519	12/81 (15%)
		RhoGAP	610..796	CDD:214618	47/189 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910