Protein Alignment tum and syd-1

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001022146.1
• Gene: syd-1 / 174230
• WormBaseID: WBGene00006363
• Length: 987
• Species: Caenorhabditis elegans
• Alignment Length: 641
• Identity: 135/641 - (21%)
• Similarity: 220/641 - (34%)
• Gaps: 194/641 - (30%)

  Fly    92 DAMESKIMAVADLLRHERNLNNETRDKLAFLHTLPSSRKRKSLNAVREDKSYGDINSTGSLL--- 153
            |.:.|:.:....|.|..|..|:..:.     ::||   :|:.:...|..|...|:.||..|.
 Worm   410 DPLLSRSLCSPILPRTLRQANDSNKS-----NSLP---RRRIMTGGRNVKWRNDVVSTSDLCGEE 466

  Fly   154 SDLSIT---HSEDDFLDVRTSKSWR--EHRPSLPKNQIPSVGNKRSRLSTGLNGSMSGTTPTTGK 213
            ||.:|:   :|...|..:...:.:|  ...|....|.|.|....|:.........|.|..|...:
 Worm   467 SDGAISAPEYSSPPFSRLTQQQQFRLSNGSPGRTVNDIFSAAEYRNWAGPYDPRGMYGPFPPGQR 531

  Fly   214 SRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGN---------E 269
            :.|.|       ||    .|.:|...|:  ::|  |:.|: |:|.:.| ||:..:         .
 Worm   532 ATRWS-------HT----YGEQRAPRTS--SLP--GRTVL-AQSLVGS-PVLPRHPPPIVQDRPS 579

  Fly   270 RIGDGLSSTP---RRSVLKEA---------TAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFS 322
            .:.|....:|   ||:.|:.|         :...||.:  :..|:|...|..:..:
 Worm   580 AVFDRYHVSPLMNRRAPLRAAGPGINVDRLSVSSLTGI--LYVHIVEGRGLKIPEK--------- 633

  Fly   323 QKTFLRGDNC---VQCQKRIRFGAVGL----RCRDCPVRCHID-----CRYLLTVSCVPQ----- 370
            ||.......|   |..|.|.|.|...:    :.|:   ..|||     .......|..||
 Worm   634 QKGLTEEMYCVLEVDEQHRARTGVSTIEQKFKWRE---TFHIDVVNATVSNFFVYSWHPQFRHKL 695

  Fly   371 TGTPTTKTMTGYVTD-------FAPSIAPM----------------------------------- 393
            ....:.|.:..:|.|       ||.::.|.
 Worm   696 CHKGSLKLLEAFVVDQLNDDRVFALNLEPRGQLIVRIGFHDLQAVFRRTVNPRLNGVFGISLSRL 760

  Fly   394 -------IPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQF--------LRGKATPHLGN 443
                   .|.::...:.|||.||:...|||.|..|..:.|.|:.:.        |..::.|
 Worm   761 VQRERRDTPIVLTRLIQEIEKRGVDYSGLYVLCGSVEKKKMLRAELESNPLGTELAAESIP---- 821

  Fly   444 TDIYVLCCCVKDFLRSLTEPLIPT---SQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLA 505
             |..|:.|.:|||||.|.||||..   ....:.|:.....|.:|.:.:::|.:..|..:.::.|.
 Worm   822 -DTNVIACLIKDFLRELPEPLISPQIHGMLLEAASVALPNDVQTNRHLVLKIIDCLQLSAKNCLL 885

  Fly   506 FLILHFQRI-AQCPVVLMPIDNISLIFGP-------TIVGYS-TPDPDQHAIYTEVFTQKQVMKA 561
            .::.|...: ...|...:....:||||.|       |...|: :|.....|:.|....|   ..:
 Worm   886 LVLDHLSTVLCSSPHNGLTPTRLSLIFAPLLFFCLDTFSPYTISPTSKMAAVRTLDINQ---ASS 947

  Fly   562 LLELPVSFWEQYIVIDPTR--------TPATVIKRVPSNKNDLLSLYATPFKGGTI 609
            .|::.:|.|       |:|        :|||..:                 |||.|
 Worm   948 SLQMILSIW-------PSRVNSESGSDSPATTCQ-----------------KGGVI 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	12/59 (20%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	54/257 (21%)
syd-1	NP_001022146.1	PDZ_signaling	123..205	CDD:238492
		C2	617..705	CDD:214577	19/101 (19%)
		RhoGAP_SYD1	753..957	CDD:239844	50/218 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910