DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and hum-7

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	NP_001248880.1	Gene:	hum-7 / 171650	WormBaseID:	WBGene00002040	Length:	1880	Species:	Caenorhabditis elegans

Alignment Length:	250	Identity:	65/250 - (26%)
Similarity:	106/250 - (42%)	Gaps:	28/250 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   332 CVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTD--------FAP 388
            |..|.:.|........|..|.:.||..|:..:|..|          .|||...|        |..
Worm  1488 CEVCNQLIWHHEKLYTCVACRISCHKKCQPKVTHPC----------QMTGKAIDPKTNGGRFFGA 1542

  Fly   389 SIAPM------IPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKE--QFLRGKATPHLGNTD 445
            |:..:      :|.|:......||.|.|...|:||.|.|..:.:::::  :......:.:|.:..
Worm  1543 SLVSIVDDDHTVPTLLDRLFFAIETRALFVEGVYRKSGSLPQVRSIRKVIESTADADSVNLEDIG 1607

  Fly   446 IYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILH 510
            ::||...||.|.|.|.||:|....:::|.|..:..|.......|...::.||:.||..|..|:.|
Worm  1608 VHVLTTLVKAFFRELAEPIIIFDLYENFLNVSEVEDMGERVRCLSVMIELLPKPNRAVLDRLMYH 1672

  Fly   511 FQRIA-QCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLE 564
            ..|:| |..|..|..:|::|||||.::........|..: .:|..|...::.|:|
Worm  1673 LARVADQEAVNKMGCNNLALIFGPCVLRRQDSAHAQEQL-NDVARQTGCVQTLIE 1726

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	9/34 (26%)
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	52/200 (26%)
hum-7	NP_001248880.1	RA	28..134	CDD:214612
		MYSc	163..936	CDD:214580
		MYSc_Myo9	181..936	CDD:276836
		C1	1234..1284	CDD:237996
		C1	1475..1523	CDD:237996	9/34 (26%)
		RhoGAP	1540..1727	CDD:295372	50/187 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910