DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and AgaP_AGAP009730

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_318814.4	Gene:	AgaP_AGAP009730 / 1279139	VectorBaseID:	AGAP009730	Length:	1581	Species:	Anopheles gambiae

Alignment Length:	502	Identity:	95/502 - (18%)
Similarity:	164/502 - (32%)	Gaps:	150/502 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSALASFDDLRRCMQVLTDGTPEEEFLR---FLRM-FEQYHE-------------KCAGYAAETA 50
            |.|:|..|..|...:..:...|.:||||   ||.. |::..|             |..|:.....
Mosquito   970 LRAMAILDTARGRQKGFSHRIPFQEFLRRYQFLAFDFDENVEMTRDNCRLLLLRLKLEGWVIGKT 1034

  Fly    51 RI----------QNELDKSLTKMGDLEG--KLFHARRIIDMEIK------ARRQAEHERDAMESK 97
            ::          |...:..:.|:..::.  :.|.|:|.:..::|      .|::....:|:.:..
Mosquito  1035 KVFLKYYNVEYLQRLYETQVKKIVKIQAMMRAFLAKRTVATKLKQVHRESIRKRQMVNQDSQDEA 1099

  Fly    98 IMAVADLLRHE------RNLNNETRDKL-----AFLHTLPSSRKRKSL-------NAVREDKSYG 144
            .:.:....|..      |.|.|:...||     .|:.......::||:       .|.|    |.
Mosquito  1100 ALKIQSAYRGHMARKKYRPLINDRTGKLDAETAEFMKPFVYRWRKKSMYQVLLQYRAAR----YQ 1160

  Fly   145 DINSTGSLLSDLSITHSEDDFLDVRTSKSW--------REHRPSLPKNQIPSVGNKRSRLSTGLN 201
            |:.:    ||.....:::.......||.:.        .:..|:|...|.|:|...|.|..   :
Mosquito  1161 DLVN----LSQQVHIYNQRLVAGFATSSNCIMLDKIDPNQRNPALLGPQRPAVWKLRFRFD---D 1218

  Fly   202 GSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIA 266
            .....||.....|..|.|..|.:..|                   :|....:|....:.|  .|.
Mosquito  1219 IPFFDTTYMCDPSSASYVYTGNDSDT-------------------EDWDAPLRRRKNLSS--EIT 1262

  Fly   267 GNERIG---DGLSSTPRRSVLKEA-TAPPLTPVNAMAPHVVAE------------SGTPLQ--HR 313
            .:.:.|   ||.....:.|:..|. ...|..|:..::||.|.|            |.||:.  :.
Mosquito  1263 KSAQKGYRMDGPGDVGQHSLANEPFHRDPSLPIKRLSPHHVVEPYAVNRPRSPIQSATPMSSVYS 1327

  Fly   314 PL---------MRNHTFSQKTFLR----GDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTV 365
            |:         :|| .||..:|..    |.......|:.:...|.:...:.|:           |
Mosquito  1328 PIPYARQSVDDIRN-KFSATSFDETGSVGTGKTAIYKKRQAPRVPMAEPEVPI-----------V 1380

  Fly   366 SCVPQTGT---PTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEARG 409
            :..||.|.   |..:          |.:.|:.|..| :.:.|:|..|
Mosquito  1381 AEFPQKGVKKRPAPQ----------PQVRPITPTKI-NPIKEMELIG 1416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	8/51 (16%)
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	7/29 (24%)
AgaP_AGAP009730	XP_318814.4	PKc_like	9..284	CDD:304357
		S_TKc	16..284	CDD:214567
		MYSc	330..1051	CDD:214580	17/80 (21%)
		MYSc_Myo21	347..1039	CDD:276848	16/68 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910