DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and AgaP_AGAP004000

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_318459.5	Gene:	AgaP_AGAP004000 / 1278822	VectorBaseID:	AGAP004000	Length:	2647	Species:	Anopheles gambiae

Alignment Length:	294	Identity:	72/294 - (24%)
Similarity:	117/294 - (39%)	Gaps:	58/294 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 HTFSQKTFLR-GDNCVQCQKRIRFGAV-GLRCRDCPVRCHIDCRYLLTVSC-------------- 367
            ||| |.|.|. ...|..||:.:.:... ||.|::|.:.||..| |..:.||
Mosquito  1843 HTF-QLTILNIATACEICQQFLLWPIERGLVCQNCKLTCHKKC-YQKSASCNKIANADPNSLLGA 1905

  Fly   368 -----------------------VPQT--GTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEA 407
                                   :|..  |.|.| .:.|..:|     ...|||.|...:..||.
Mosquito  1906 GGSGSAVVAGGCGPDGQPLYGGGIPTKLFGVPLT-ALCGNSSD-----GVKIPAQINKLIMMIEM 1964

  Fly   408 RGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLG-------NTDIYVLCCCVKDFLRSLTEPLI 465
            .||...|:||.|....:.|.||.:..|...:...|       :.:::||...:|.|||.:.|||:
Mosquito  1965 HGLYSEGIYRKSGVSSKIKDLKAKMDRAVTSADGGGGEMDFESYNVHVLTNVLKSFLREMPEPLL 2029

  Fly   466 PTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIAQCPVV-LMPIDNISL 529
            ...::.||..|....|.......|:..||::|.|:......||.|...:|:.... .|...::::
Mosquito  2030 TFDRYDDFLRAADLSDGSDRVQTLLSLVKKIPPAHHCLFERLIFHLALVAKLEQYNRMSASSLAI 2094

  Fly   530 IFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALL 563
            :|.|.::..:...|.|.:: .::..|.:.|:.|:
Mosquito  2095 VFAPCVLRTNRYVPAQDSL-NDIGRQTKCMETLI 2127

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	17/49 (35%)
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	49/191 (26%)
AgaP_AGAP004000	XP_318459.5	RA	16..85	CDD:214612
		MYSc	120..779	CDD:214580
		MYSc_Myo9	130..771	CDD:276836
		IQ	836..854	CDD:197470
		C1	1602..1643	CDD:237996
		C1	1843..1891	CDD:237996	17/49 (35%)
		RhoGAP	1934..2127	CDD:295372	51/199 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910