Protein Alignment tum and arhgap21a

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001340279.1
• Gene: arhgap21a / 101883923
• ZFINID: ZDB-GENE-090918-5
• Length: 1939
• Species: Danio rerio
• Alignment Length: 633
• Identity: 116/633 - (18%)
• Similarity: 216/633 - (34%)
• Gaps: 202/633 - (31%)

  Fly    84 RRQAEHERDAMESKIMAVADLLRHERN----LNN--ETRDKLAFLHTLPSSRKRKSLNAVREDKS 142
            |||..|::|::...|:.........|:    |:|  |.|...:..||......||:::...||..
Zfish   845 RRQLSHDQDSLRLTILESDSKTERSRSFDEGLDNYREERRGRSIKHTHGFKGLRKAVDRCSEDSG 909

  Fly   143 ---------YGDINSTGSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLST 198
                     :.|....|||.  ....:||.......:.:||::....|..:.:....:||
Zfish   910 SRRDSNSDVFTDATKEGSLY--FRQLNSEKSKRVGSSMRSWKQIYAVLRGHCLYLYKDKR----- 967

  Fly   199 GLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVG---------------------QGAERFCATTK 242
                  .|.|....:.....:.|.::...:|:.                     |..:|....:.
Zfish   968 ------DGQTNANSQIEEEPLPISIKACLIDISYSDTKRKNVLRLTTSDCEYLFQAEDREEMLSW 1026

  Fly   243 VTIPQDGQGVIRAESTIESLPVIAGNERI-----------------------------------G 272
            :.:.|:...:....:|:.|..:|  |.:|                                   |
Zfish  1027 IRVIQENSNLDEENATVTSTDLI--NRKIKEYNTLMSPPSSKTEPSPKASRQSLSIRQTLLGGKG 1089

  Fly   273 DGLSSTP--------RRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQK----- 324
            :..:::|        |:::.|:.|:||            .:.||..:..|.:....|.:|
Zfish  1090 ENKATSPHSPNKEHDRKAMHKDETSPP------------KDKGTWRKGIPGLMRKPFEKKPSPGV 1142

  Fly   325 TFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPS 389
            ||                  |:|..|||                     |.....
Zfish  1143 TF------------------GVRLDDCP---------------------PAQNNR---------- 1158

  Fly   390 IAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQF-LRGKATPHLGN---TDIYVLC 450
               .:|.::..|.|.:|.|||...|:||:..:......::|:. .:|.|...:.:   .|:.|:.
Zfish  1159 ---FVPLIVEVCCNLVEERGLEYTGIYRVPGNNAAISIMQEELNNKGMADIDIQDDKWKDLNVIS 1220

  Fly   451 CCVKDFLRSLTEPLIPTSQWKDF--ANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQR 513
            ..:|.|.|.|.|||....::.||  .|.:::|..:.  .:|.:.:.:||..:.:||.||..|.:.
Zfish  1221 SLLKSFFRKLPEPLFTNERYADFIDGNRIEDPVERL--KVLKRLLHELPDHHYETLKFLSAHLKT 1283

  Fly   514 IAQ-CPVVLMPIDNISLIFGPTIVGYS--------TPDPDQHAIYTEVFTQKQVMKALLELPVSF 569
            :|: .....|...|::::||||:|..|        |..|||:.|              :|..:..
Zfish  1284 VAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKI--------------VETLIQH 1334

  Fly   570 WEQYIVIDPTRTPATVIKR--------VPSNKNDLLSLYATPFKGGTI 609
            ::.:...:....|.|.::.        ||:..:.|.::..|....|.:
Zfish  1335 YDWFFTEEGDNEPTTTVQEESAVESQPVPNIDHLLTNIGRTGTSPGEV 1382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	9/52 (17%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	49/203 (24%)
arhgap21a	NP_001340279.1	PDZ_signaling	53..128	CDD:238492
		PH_ARHGAP21-like	923..1037	CDD:269955	17/126 (13%)
		RhoGAP_ARHGAP21	1143..1339	CDD:239860	57/263 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910