Protein Alignment tum and arhgap35

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_004917008.1
• Gene: arhgap35 / 100498460
• XenbaseID: XB-GENE-999477
• Length: 1472
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 120/585 - (20%)
• Similarity: 198/585 - (33%)
• Gaps: 199/585 - (34%)

  Fly    70 LFHARRIIDMEIKARRQAEHE-RDAMESKIMAVADLLRHERNLNNE---------------TRDK 118
            ||.....|...||..|:.|.. .:.:|||             |||:               |:.:
 Frog   990 LFQNEPNIAAPIKFTRELEETVMNTLESK-------------LNNKVPPPLKPKPPIPYEITKPE 1041

  Fly   119 LAFLHTLPSSRKRKSLNAVR-------EDKSYGDINSTGSLLSDLSITHSEDDFLDVRTSKSWRE 176
            |::|.|......||||.::.       :...|.:               ..|..:..|..:   |
 Frog  1042 LSYLDTGARDGHRKSLTSINWPPLEAFDPSDYAE---------------PMDSVVKPRNQE---E 1088

  Fly   177 HRPSLP----KNQIPSVGNKRSRLSTGL-NGSMSG---------------TTPT--------TGK 213
            :..|:|    :.:|.::.|.....|.|. |||.|.               |.|.        .||
 Frog  1089 NIYSVPHDSTQGKIITIRNTNKPQSNGSGNGSDSDMDTNSLERARKASIVTKPVLYRTKCAKLGK 1153

  Fly   214 --SRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGLS 276
              |.|||:.:|.:.....:.:..|           :.|....:.:||..|..        .||
 Frog  1154 FSSYRSSLSVGSDDEPGPIRRKEE-----------ETGTQGTKGDSTTNSYE--------ADG-- 1197

  Fly   277 STPR-RSVLK--EATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQKR 338
            ..|| |::|:  ..|...:.|                :.||.:...|:....|
 Frog  1198 EDPRKRNILRSLRRTTKKVKP----------------KPRPSLTKATWESNYF------------ 1234

  Fly   339 IRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVN 403
                                             |.|    ::..||...|     ||..|..||.
 Frog  1235 ---------------------------------GFP----LSSVVTSERP-----IPVFIEKCVE 1257

  Fly   404 EIEA--RGLTEVGLYRLSSSEREYKALKEQFLRGKATPH---LGNTDIYV--LCCCVKDFLRSLT 461
            .|||  .|:|..|:||:|.::.|.::|:.||    ...|   |...|..|  :...:|.|...|.
 Frog  1258 YIEATGEGMTTEGIYRVSGNKSEMESLQRQF----DQDHNLDLAEKDFTVNTVAGALKSFFSELP 1318

  Fly   462 EPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIAQ-CPVVLMPID 525
            :||:|.:...:...|.:..|.:.....:...:|:.|:.|.:...::|.|..|::| ..:.||..:
 Frog  1319 DPLVPYNMQAELVEAYKINDLEHKLQAMKDLLKKFPKENHEIFKYVISHLNRVSQHHHINLMTSE 1383

  Fly   526 NISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSFWEQYIVID------PTRTPAT 584
            |:|:.|.||::   .||.......|...|.:.:::..::....|:.|.:.:|      |:..|.|
 Frog  1384 NLSICFWPTLM---RPDFTTMDALTATRTYQTIIELFIQQCPFFFYQRLPVDLPIPSSPSTPPLT 1445

  Fly   585  584
             Frog  1446  1445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	2/47 (4%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	51/196 (26%)
arhgap35	XP_004917008.1	Ras_like_GTPase	29..245	CDD:206648
		Ras	<158..247	CDD:395024
		RhoGAP-FF1	261..340	CDD:406821
		FF	429..>470	CDD:128718
		FF	485..538	CDD:128718
		pseudoGTPaseD_p190RhoGAP	589..760	CDD:425412
		PHA03151	1036..1225	CDD:177546	46/243 (19%)
		RhoGAP_p190	1234..1420	CDD:239838	54/246 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910