DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and chn2

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_002933428.2	Gene:	chn2 / 100496459	XenbaseID:	XB-GENE-950874	Length:	467	Species:	Xenopus tropicalis

Alignment Length:	308	Identity:	80/308 - (25%)
Similarity:	143/308 - (46%)	Gaps:	22/308 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   269 ERIGDGLSSTPRRSVLKEAT--APPLTPVNAMAPH-VVAESGTPLQHRPLMRNHTFSQKTFLRGD 330
            ::|...||.|...|..|..|  :..:..:.::... .:|::.   .|....:.|.|...|| ||.
Frog   164 DKITRRLSRTKNESKRKTVTNESKSVDKITSLVRRAAIAKND---NHFNYEKAHNFKVHTF-RGP 224

  Fly   331 N-CVQCQKRIRFG--AVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAP 392
            : |..| ....:|  |.|:||.||.:..|..|...:...|.|.. ....|..:..:|....:...
Frog   225 HWCEYC-ANFMWGLIAQGVRCSDCGLNVHKQCSKYVPNDCQPDL-KRIKKVYSCDLTTLVKAHNT 287

  Fly   393 MIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNT---DIYVLCCCVK 454
            ..|.::..|:.|||.|||...||||:|......:.:|..|.|......:.:|   ||.::...:|
Frog   288 PRPMVVDMCIQEIEGRGLKSEGLYRVSGFTEHIEDVKMSFDRDGDRADISSTLYPDINIITGALK 352

  Fly   455 DFLRSLTEPLIPTSQWKDF--ANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIA-Q 516
            .:.|.|..|:|....:..|  |:.:.|.|.:.  :.:.:::..||.|:.:||.||::|.:::| .
Frog   353 LYFRDLPIPVITYDTYYKFMEASKISNADERL--EAIHEALMLLPPAHYETLRFLMIHLKKVALN 415

  Fly   517 CPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLE 564
            ....||..:|:.::||||::  ..|:.:..|...::..|||:::.|::
Frog   416 EKDNLMGSENLGIVFGPTLM--RPPEENALASLNDMRHQKQIVQLLIQ 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	17/50 (34%)
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	51/190 (27%)
chn2	XP_002933428.2	SH2_a2chimerin_b2chimerin	52..138	CDD:198215
		C1_betaCHN	209..269	CDD:410407	19/62 (31%)
		RhoGAP_chimaerin	274..467	CDD:239837	51/192 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910