DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and arhgap40

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_004918589.2	Gene:	arhgap40 / 100493159	XenbaseID:	XB-GENE-6050151	Length:	644	Species:	Xenopus tropicalis

Alignment Length:	158	Identity:	50/158 - (31%)
Similarity:	70/158 - (44%)	Gaps:	22/158 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   392 PMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQ---------FLRGKATPHLGNTDIY 447
            |:|...|..|   ||..|:...|:.|:|.|:...|.|:::         |......||    |..
Frog   308 PLILQAIFTC---IEKNGMEIQGILRISGSQARIKNLQQRLEKDFYDGLFSWDDVHPH----DAS 365

  Fly   448 VLCCCVKDFLRSLTEPLIPTSQWKDFANAVQN-PDTKTAQDMLVKSVKQLPQANRDTLAFLILHF 511
            .|   :|.|||.|..||: |:|:.....|||| .|.|.....|...:..||:.||.||..|:...
Frog   366 GL---LKLFLRELPAPLL-TTQYLPAFTAVQNIVDLKQRLQALNLLILILPEPNRSTLKALLEFL 426

  Fly   512 QRIAQCPVV-LMPIDNISLIFGPTIVGY 538
            |::|..... ||.:.|:|.|..|.:..|
Frog   427 QKVAAMEKTNLMSLWNVSTILAPNLFLY 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	50/158 (32%)
arhgap40	XP_004918589.2	RhoGAP	286..497	CDD:413382	50/158 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910