Protein Alignment tum and arhgap12

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_004915509.1
• Gene: arhgap12 / 100493129
• XenbaseID: XB-GENE-961971
• Length: 824
• Species: Xenopus tropicalis
• Alignment Length: 606
• Identity: 128/606 - (21%)
• Similarity: 220/606 - (36%)
• Gaps: 177/606 - (29%)

  Fly    38 YHEKC------------AGYAAE------TARIQNELDKSLTKMGDLEGKLFHARRIIDMEIKAR 84
            ||..|            .|::.|      |..|.::.::...|..|.:|:.::
 Frog   307 YHSTCDNQSDSQYGSPPRGWSEELDQHGHTTFINDQTNEKWIKHVDDQGRPYY------------ 359

  Fly    85 RQAEHERDAME-SKIMAVADLLRH---ERNLNNETRDKLAFLHTLPSSRKRKSLNAVREDKSYGD 145
            ..|:..|...| .|..|....||.   .|:|:.:.:|.:.|     :..:..::.....||
 Frog   360 YSADGSRSEWELPKYNATLQPLREITKSRSLDRKLQDPIVF-----TKWRHSTILLDTNDK---- 415

  Fly   146 INSTGSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGL--NGS----- 203
                     |.|.|...|            |..|..||.|:.........|.|.:  ||.
 Frog   416 ---------DSSATSKPD------------ETSPPSPKQQVTDQEKYGVLLVTKITENGKKVRKN 459

  Fly   204 -MSGTTPTTGKS---RRSSVG--IGVEQ----HTVDVGQGAERFCATTKVTIPQDGQGVIRAEST 258
             ||..|...|.:   :.::.|  .|..|    .|||:...:..:.:..|    ...:.||..::|
 Frog   460 WMSSWTVLKGTTLLLQANAAGWKFGGNQSKPEFTVDIKGASVDWASKDK----SSKKNVIELKTT 520

  Fly   259 IESLPVIAGNERIGDGLSSTPRRSVLKE---------ATAP-----------PLTPVNAMAPHVV 303
                   :|.|.:....|.|    |:|:         .|.|           |.:||:   .|..
 Frog   521 -------SGTELLIQSDSDT----VIKDWYTAFCNTTGTTPGDLEEACEDNVPESPVD---KHGK 571

  Fly   304 AESGTPLQH-RPLMRNHTFSQKTFLRGDNCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSC 367
            .:......| |...:|.:|.....:  ||..|.:.:.:..                 ::|
 Frog   572 EKFDKEKDHDRDSKKNRSFKPANSI--DNAEQKKTKTKLK-----------------KFL----- 612

  Fly   368 VPQTGTPTTKTM--TGYVTD--FAPSIAPM-------IPALIVHCVNEIEARGLTEVGLYRLSSS 421
               |..||.:.:  .||:.|  |..|:|.:       :|..:..|:..:|.:||...||||:|.:
 Frog   613 ---TRRPTMQAVREKGYIKDPVFGSSLASLCQRENTTVPNFVKMCIEHVEEQGLDVDGLYRVSGN 674

  Fly   422 EREYKALKEQFLRGKATPH-----LGNT---DIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQ 478
            ....:.|:      .|..|     |.::   ||:|:...:|.|.|.|.|||...|.:.||.||::
 Frog   675 LAVIQKLR------FAVTHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFSHFNDFVNAIK 733

  Fly   479 NPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIAQC-PVVLMPIDNISLIFGPTIVGYSTPD 542
            . :.|.....:...:||||:.|.||:..|..|.:::.:. ....|...:::::||||::   .|:
 Frog   734 Q-EPKLRVQAIKDLIKQLPKPNHDTMQALFKHLKKVVETGEKNRMTYQSLAIVFGPTLL---KPE 794

  Fly   543 PDQHAIYTEVFTQKQVMKALL 563
            .:...|......|.|:::.:|
 Frog   795 SETGNIAIHTVYQNQIVELIL 815

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	5/47 (11%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	55/201 (27%)
arhgap12	XP_004915509.1	SH3	<26..72	CDD:388381
		SH3-WW_linker	69..249	CDD:374675
		WW	255..282	CDD:238122
		WW	347..372	CDD:366073	6/36 (17%)
		PH_ARHGAP9-like	439..545	CDD:270053	24/120 (20%)
		RhoGAP_ARHGAP27_15_12_9	632..817	CDD:239868	52/194 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910