DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tum and arhgap22

DIOPT Version :9

Sequence 1:	NP_610912.2	Gene:	tum / 36538	FlyBaseID:	FBgn0086356	Length:	625	Species:	Drosophila melanogaster
Sequence 2:	XP_002940376.2	Gene:	arhgap22 / 100127847	XenbaseID:	XB-GENE-5807514	Length:	544	Species:	Xenopus tropicalis

Alignment Length:	201	Identity:	51/201 - (25%)
Similarity:	92/201 - (45%)	Gaps:	17/201 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   395 PALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNTDIYVLCCCVKDFLRS 459
            |.::..||:.|...||.|.||:||.......|.|::.|..|.......:||::.:...:|.:||.
Frog    71 PLVVEQCVDFIRENGLQEEGLFRLPGQATLVKELQDTFDSGGKPTFDKSTDVHTVASLLKLYLRE 135

  Fly   460 LTEPLIPTSQWKDF---ANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRI-AQCPVV 520
            |.||:||.|:::||   |:.:.....:..|::.: .:|.||..|.:.|.::......: :.....
Frog   136 LPEPVIPFSRYQDFLRCAHILSGDQGEGTQELSI-LIKSLPPVNYNLLKYICSFLDEVQSYSDTN 199

  Fly   521 LMPIDNISLIFGPTIVGYSTPDP---------DQHAIYTEVFTQKQVMKAL-LELPVSFWEQYIV 575
            .|.:.|::.:|.|.|:.....||         .||.:...:.....:.:|: .:.||....|.
Frog   200 KMNVQNLATVFAPNILRPKQQDPVALIEGASLIQHLLTILIHENHWIFQAVSADSPVGVSVQQ-- 262

  Fly   576 IDPTRT 581
            ||.|::
Frog   263 IDNTQS 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996
tum	NP_610912.2	RhoGAP_MgcRacGAP	381..570	CDD:239847	47/188 (25%)
arhgap22	XP_002940376.2	PH-like	<16..52	CDD:388408
		RhoGAP	53..247	CDD:383032	44/176 (25%)
		Myosin_tail_1	<446..>521	CDD:366712
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910