Protein Alignment tum and arhgap45

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: XP_012822956.2
• Gene: arhgap45 / 100125789
• XenbaseID: XB-GENE-990078
• Length: 1114
• Species: Xenopus tropicalis
• Alignment Length: 670
• Identity: 138/670 - (20%)
• Similarity: 237/670 - (35%)
• Gaps: 176/670 - (26%)

  Fly    26 EEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHARRIIDMEIKARRQAEHE 90
            :.||:.:.|..|.|||      ....::.:..::..|:.:.|..|..||     :...:|..|||
 Frog   356 QTFLQPINMRRQEHEK------RRKEVKEQWQRAQRKLMEAESNLRKAR-----QAYMQRSEEHE 409

  Fly    91 R----------DAMESKIMAVADLLRHERNLNNETRDKLAFLHTLPSSRKRK-------SLNAVR 138
            |          :...|...::....|.|....|...:.:|...|..:..|.:       .:|.:|
 Frog   410 RALYNATRAEEEQSHSGTRSLDKKRRAEEEAKNRAEEAMATYRTCIADAKTQKQELEDVKVNVLR 474

  Fly   139 EDKSYGDINSTGSLLSDLSITHSED---------------------------------------- 163
            :.:..  |..:..:|...:|::.:.
 Frog   475 QLQEL--IKQSDQILRSATISYYQSMHMQTAPLPVGFQTLCESSKLYDLGQQYASYVRQLGAVNE 537

  Fly   164 -----DFLDVRTSKSW----REHRPSLPKNQIPSVGNKRSRLSTGLNGSMSGTTPTTGKSRRSSV 219
                 ||.......:|    |..:.|.....|||..||          .:||.....  .||.
 Frog   538 PETTYDFQPYTPQITWSPCIRSRKSSFNSQDIPSSENK----------EISGEERVV--ERRG-- 588

  Fly   220 GIGVEQH-----TVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGLSSTP 279
            |.|.:.|     .:..|..|   .:.|....|:...........::...:.|..|:..:|||.:.
 Frog   589 GRGHQVHKSWPTAITEGDPA---VSNTGTAFPEKLHQPSSPIDIVDQKRLSASFEQSINGLSGSL 650

  Fly   280 RRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGDNCVQCQKRIRFGAV 344
            .   :..:|.|...         :..|...|.|| |.:..|.|:        |.:|...:.|  .
 Frog   651 E---VPHSTGPFRN---------IGLSRAALTHR-LRKLRTPSK--------CRECNSYVYF--Q 692

  Fly   345 GLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTG----YVTDFAPSI--AP-MIPALIVHCV 402
            |..|.:|.:.||..|...|.:.|       ..|.:.|    :..||:.:.  :| .||.||..||
 Frog   693 GAECEECSLACHKKCLETLAIQC-------GHKKLQGRLLLFGRDFSETALRSPDHIPFLIRKCV 750

  Fly   403 NEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNTDIYVLCCCVKDFLRSLTEPLIPT 467
            :|||.|.||..|:||::..:...:.|.:.|..||....|.....:.|...:|.:||.|.|||||.
 Frog   751 SEIEERALTMKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDLSNVLKLYLRQLPEPLIPF 815

  Fly   468 SQW-------KDFANAVQ----------NPDTKTAQDMLVKSVKQ----LPQANRDTLAFLILHF 511
            ..:       |:....::          .|:|:.....:|..:|:    ||..||.||.:|:.|.
 Frog   816 RLYNGLMGLAKESLRGIETGKGSRLQDKGPNTEPEVLSMVVQLKELLQDLPVENRTTLQYLVKHL 880

  Fly   512 QRIA-QCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSFWEQYIV 575
            .|:: |..:..|...|:.::|||.::   .|.|....:         .:.:|::.|    .|..:
 Frog   881 CRVSEQEQLNKMSPSNLGIVFGPALM---RPRPTDATV---------SLSSLVDYP----HQARI 929

  Fly   576 IDPTRTPATVIKRVPSNKND 595
            ::......:.|.:.|::.:|
 Frog   930 VETLIIFYSTIFQEPASSSD 949

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	12/47 (26%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	58/217 (27%)
arhgap45	XP_012822956.2	PRK12495	<22..151	CDD:183558
		BAR	289..515	CDD:416402	29/171 (17%)
		C1_GMIP-like	669..719	CDD:410366	17/67 (25%)
		RhoGAP	727..936	CDD:413382	58/224 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910