Protein Alignment CG6553 and Lrp1b

DIOPT Version :10

• Sequence 1: NP_610911.1
• Gene: CG6553 / 36537
• FlyBaseID: FBgn0033880
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_006498522.1
• Gene: Lrp1b / 94217
• MGIID: 2151136
• Length: 4668
• Species: Mus musculus
• Alignment Length: 169
• Identity: 55/169 - (32%)
• Similarity: 71/169 - (42%)
• Gaps: 38/169 - (22%)

  Fly    21 TICLG---------------SQNATSCG--------HRCGGGD-------CIQLDQLCDGSANCL 55
            |:||.               .:|.|:|.        |.|..|:       |||....|||..:||
Mouse   838 TLCLAIPAGRVCACADNQLLDENGTTCTFNPEEIRFHICKPGEFRCKNKHCIQARWKCDGDDDCL 902

  Fly    56 DGSDETVAMCEKVWCPGYAFRCSYGACIASTAVCDGVQDCVDGSDEQGWLCRAQMQQANCDNWEM 120
            |||||....|....||...|:|....||....:|||..||....||....|.|:..||:    :.
Mouse   903 DGSDEDSVTCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQAD----QF 963

  Fly   121 YCSSGQCMTYSKLCDGIRDCRDGDDELES----LCEGVT 155
            .|.:|:|:..:.|||...||.|..||:.|    .||.:|
Mouse   964 SCGNGRCIPTAWLCDREDDCGDQTDEVASCEFPTCEPLT 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6553	NP_610911.1	LDLa	34..60	CDD:197566	14/32 (44%)
		LDLa	70..101	CDD:197566	11/30 (37%)
		LDLa	115..146	CDD:197566	9/30 (30%)
Lrp1b	XP_006498522.1	LDLa	63..95	CDD:238060
		LDLa	107..140	CDD:197566
		FXa_inhibition	194..224	CDD:464251
		LY	314..346	CDD:214531
		LY	350..392	CDD:214531
		LY	394..435	CDD:214531
		FXa_inhibition	506..547	CDD:464251
		Ldl_recept_b	599..639	CDD:459654
		LY	622..661	CDD:214531
		LY	668..717	CDD:214531
		LY	718..760	CDD:214531
		FXa_inhibition	829..864	CDD:464251	5/25 (20%)
		LDLa	917..950	CDD:238060	13/32 (41%)
		LDLa	957..989	CDD:197566	11/35 (31%)
		LDLa	1000..1033	CDD:238060	1/3 (33%)
		LDLa	1037..1070	CDD:238060
		LDLa	1084..1119	CDD:238060
		Ldl_recept_a	1131..1162	CDD:395011
		LDLa	1167..1202	CDD:238060
		FXa_inhibition	1207..1243	CDD:464251
		YncE	1313..1537	CDD:442618
		LY	1358..1398	CDD:214531
		LY	1402..1445	CDD:214531
		Ldl_recept_b	1649..1689	CDD:459654
		LY	1672..1714	CDD:214531
		Ldl_recept_b	1736..1773	CDD:459654
		LY	<1766..1797	CDD:214531
		FXa_inhibition	1869..1905	CDD:464251
		NHL	1944..2169	CDD:302697
		NHL repeat	1944..1983	CDD:271320
		LY	1978..2018	CDD:214531
		NHL repeat	1988..2025	CDD:271320
		NHL repeat	2029..2070	CDD:271320
		Ldl_recept_b	2039..2080	CDD:459654
		LY	2064..2106	CDD:214531
		NHL repeat	2073..2111	CDD:271320
		NHL repeat	2120..2159	CDD:271320
		FXa_inhibition	2178..2213	CDD:464251
		Ldl_recept_b	2361..2403	CDD:459654
		LY	2386..2428	CDD:214531
		LDLa	2545..2574	CDD:238060
		LDLa	2583..2617	CDD:238060
		LDLa	2622..2656	CDD:238060
		LDLa	2676..2705	CDD:238060
		LDLa	2713..2747	CDD:238060
		LDLa	2751..2784	CDD:238060
		LDLa	2791..2824	CDD:197566
		LDLa	2875..2908	CDD:197566
		LDLa	2922..2956	CDD:238060
		FXa_inhibition	2968..2997	CDD:464251
		EGF_CA	2999..3033	CDD:214542
		LY	3066..3110	CDD:214531
		LY	3111..3149	CDD:214531
		LY	3154..3195	CDD:214531
		LY	3198..3237	CDD:214531
		FXa_inhibition	3308..3344	CDD:464251
		LDLa	3348..3379	CDD:197566
		LDLa	3388..3422	CDD:238060
		LDLa	3427..3462	CDD:238060
		LDLa	3467..3502	CDD:238060
		LDLa	3507..3541	CDD:238060
		LDLa	3546..3580	CDD:238060
		LDLa	3584..3618	CDD:238060
		LDLa	3625..3659	CDD:238060
LDLa	3663..3698	CDD:238060
LDLa	3705..3737	CDD:238060
LDLa	3746..3782	CDD:238060
LDLa	3793..3827	CDD:238060
EGF_CA	3875..3909	CDD:214542
NHL	3972..4204	CDD:302697
NHL repeat	4002..4039	CDD:271320
NHL repeat	4060..4098	CDD:271320
Ldl_recept_b	4070..4111	CDD:459654
LY	4094..4133	CDD:214531
NHL repeat	4148..4186	CDD:271320
EGF_CA	4281..4315	CDD:238011