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Protein Alignment CG6553 and SORL1

DIOPT Version :10

Sequence 1:	NP_610911.1	Gene:	CG6553 / 36537	FlyBaseID:	FBgn0033880	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_003096.2	Gene:	SORL1 / 6653	HGNCID:	11185	Length:	2214	Species:	Homo sapiens

Alignment Length:	266	Identity:	77/266 - (28%)
Similarity:	97/266 - (36%)	Gaps:	99/266 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NATSCGH-------RCGGGDCIQLDQLCDGSANCLDGSDETVAMCEKVWCPGYAFRCSYGACIAS 85
            |.|:..|       :|..|.||.....|||..:|.|||||....|||. |.|  |||..|.||.|
Human  1191 NCTAIYHTCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKK-CNG--FRCPNGTCIPS 1252

  Fly    86 TAVCDGVQDCVDGSDEQGW--LCRAQMQQANCDNWEMYCSSGQCMTYSKLCDGIRDCRDGDD--- 145
            :..|||::||.||||||..  ||...|... |.|.:      ||:.:|.:||||..||||.|
Human  1253 SKHCDGLRDCSDGSDEQHCEPLCTHFMDFV-CKNRQ------QCLFHSMVCDGIIQCRDGSDEDA 1310

  Fly   146 ---------ELESLCE--------GVTIPTTTVSSTTSTTTESSIHRITPTVPVTRKASRPNPLQ 193
                     |...:|:        ||.|.............:.|           .:|:..||.:
Human  1311 AFAGCSQDPEFHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYS-----------DEANCENPTE 1364

  Fly   194 ------------ENGECVVPQLPNVMVKHFTDAILTVGSRVANGTRIYYDCPAEHRLKGENQNIC 246
                        |||.|:    ||                               |.|.:.:|.|
Human  1365 APNCSRYFQFRCENGHCI----PN-------------------------------RWKCDRENDC 1394

  Fly   247 QDALWA 252
            .|  |:
Human  1395 GD--WS 1398

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.