Protein Alignment CG6553 and Vldlr

DIOPT Version :10

• Sequence 1: NP_610911.1
• Gene: CG6553 / 36537
• FlyBaseID: FBgn0033880
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_038731.2
• Gene: Vldlr / 22359
• MGIID: 98935
• Length: 873
• Species: Mus musculus
• Alignment Length: 294
• Identity: 53/294 - (18%)
• Similarity: 95/294 - (32%)
• Gaps: 79/294 - (26%)

  Fly    69 LVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLS 133
            |..|:.||:..|...:...:.|..:....|:|.:.:.|...:.: ..|.|:.:..  :.||.|::
Mouse   646 LSTRILGGIWWFFTLIIISSYTANLAAFLTVERMDSPIDSADDL-AKQTRIEYGA--VRDGSTMT 707

  Fly   134 DYNIQKESTLH-------------LVLRLRGGMQIFVKT-----LTGKTITLEVEPSDTIENVKA 180
            .:...|.||..             ||...:.|:...:.|     :...:|....:.:..:..|..
Mouse   708 FFKKSKISTYEKMWAFMSSRKNTALVKNSKDGITRVLTTDYALLMESTSIEYITQRNCNLTQVGG 772

  Fly   181 KIQDK---EGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTIT 242
            .|..|   .|.|        .|....|..|::...:|:|..||:
Mouse   773 LIDSKGYGVGTP--------IGSPYRDKVTIAILQLQEEGKLHM--------------------- 808

  Fly   243 LEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQI 307
                       :|.|.....|.|.            ||.:..|...::....:.:|  |..|:.:
Mouse   809 -----------MKEKWWRGNGCPE------------EDSKEASALGVENIGGIFIV--LAAGLVL 848

  Fly   308 FVKTLTGKTITLEVEPSDTIENVK-AKIQDKEGI 340
            .|....|:.|....:.||..|.|. :.:.:..||
Mouse   849 SVFVAIGEFIYKSHKNSDIEECVSFSAVMEDLGI 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6553	NP_610911.1	LDLa	34..60	CDD:197566
		LDLa	70..101	CDD:197566	6/30 (20%)
		LDLa	115..146	CDD:197566	8/43 (19%)
Vldlr	NP_038731.2	LDLa	33..67	CDD:238060
		LDLa	71..103	CDD:197566
		Ldl_recept_a	111..149	CDD:395011
		Ldl_recept_a	153..188	CDD:395011
		Ldl_recept_a	192..224	CDD:395011
		Ldl_recept_a	237..273	CDD:395011
		Ldl_recept_a	276..312	CDD:395011
		Ldl_recept_a	320..350	CDD:395011
		FXa_inhibition	360..394	CDD:464251
		EGF_CA	396..426	CDD:214542
		LDL-receptor class B 1	439..480
		LDL-receptor class B 2	481..524
		Ldl_recept_b	481..522	CDD:459654
		LDL-receptor class B 3	525..567
		Ldl_recept_b	527..565	CDD:459654
		LDL-receptor class B 4	568..611
		Ldl_recept_b	568..608	CDD:459654
		LY	592..634	CDD:214531
		LDL-receptor class B 5	612..654		3/7 (43%)
		LDL-receptor class B 6	655..697		7/42 (17%)
		Ldl_recept_b	655..695	CDD:459654	6/40 (15%)
		FXa_inhibition	706..749	CDD:464251	7/42 (17%)
		Clustered O-linked oligosaccharides	751..790		7/46 (15%)
		Endocytosis signal. /evidence=ECO:0000255	832..837		0/4 (0%)