Protein Alignment CG6553 and Lrp8

DIOPT Version :10

• Sequence 1: NP_610911.1
• Gene: CG6553 / 36537
• FlyBaseID: FBgn0033880
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: XP_011238756.1
• Gene: Lrp8 / 16975
• MGIID: 1340044
• Length: 1010
• Species: Mus musculus
• Alignment Length: 239
• Identity: 69/239 - (28%)
• Similarity: 95/239 - (39%)
• Gaps: 76/239 - (31%)

  Fly    36 CGGGDCIQLDQLCDGSANCLDGSDETVAMCEKVWCPG----YAFRCSYGACIASTAVCDGVQDCV 96
            |..|:||.|...|||..:|.|.|||  |.|.   .||    ..|:|..|.|:.:...|:..:||.
Mouse   259 CRSGECIHLGWRCDGDRDCKDKSDE--ADCS---APGPCRENEFQCGDGTCVLAIKRCNQERDCP 318

  Fly    97 DGSDEQGWLCRAQMQQANCDNWEMY-CSSGQCMTYSKLCDGIRDCRDGDDELESLCEGVTIPTTT 160
            |||||.|.|     |::.|:....: |.||:|:...|:||..|||||..||.:.:|
Mouse   319 DGSDEAGCL-----QESTCEGPRRFQCKSGECVDGGKVCDDQRDCRDWSDEPQKVC--------- 369

  Fly   161 VSSTTSTTTESSIHRITPTVPVTRKASRPNPLQE----NGECVVPQLPNVMVKHFTDAILTVGSR 221
                           :.|:.|..|:  .|..|.|    ||.|                     |.
Mouse   370 ---------------VAPSFPGNRR--HPRGLNECLHNNGGC---------------------SH 396

  Fly   222 VANGTRIYYD--CPAEHRLKGENQNICQDALWARKFPYCETPQA 263
            :....:|.::  |||..:|.  :|..|.|      ...|:.|.|
Mouse   397 ICTDLKIGFECTCPAGFQLL--DQKTCGD------IDECQDPDA 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6553	NP_610911.1	LDLa	34..60	CDD:197566	11/23 (48%)
		LDLa	70..101	CDD:197566	12/34 (35%)
		LDLa	115..146	CDD:197566	13/31 (42%)
Lrp8	XP_011238756.1	LDLa	41..75	CDD:238060
		LDLa	79..111	CDD:197566
		LDLa	121..157	CDD:238060
		LDLa	200..232	CDD:197566
		LDLa	256..286	CDD:238060	14/28 (50%)
		LDLa	292..326	CDD:238060	12/33 (36%)
		Ldl_recept_a	330..366	CDD:395011	15/35 (43%)
		FXa_inhibition	387..421	CDD:464251	10/56 (18%)
		EGF_CA	423..453	CDD:214542	4/16 (25%)
		LY	492..527	CDD:214531
		LY	537..578	CDD:214531
		Ldl_recept_b	599..639	CDD:459654
		LY	623..665	CDD:214531
		Ldl_recept_b	686..726	CDD:459654
		FXa_inhibition	744..781	CDD:464251