DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Echs1 and Cdyl2

DIOPT Version :9

Sequence 1:	NP_610910.1	Gene:	Echs1 / 36536	FlyBaseID:	FBgn0033879	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_083717.1	Gene:	Cdyl2 / 75796	MGIID:	1923046	Length:	503	Species:	Mus musculus

Alignment Length:	243	Identity:	59/243 - (24%)
Similarity:	109/243 - (44%)	Gaps:	17/243 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 RFSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKALNALCNGLMKELSTALQQFSKDKTISAIVL 92
            |:|.....:|..:....|..|.....::..::....|||...:|||:..||...:.|.: ..::|
Mouse   234 RYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDS-KLLLL 297

  Fly    93 TGSEKAFAAGADIKEMVGNTYSQCIQGNFLNDWTEVART-----------QKPIIAAVNGYALGG 146
            :.....|.:|.|...::|.     :..:...:.|.:|..           :|||:.|:||.|||.
Mouse   298 SAVGSVFCSGLDYSYLIGR-----LSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGL 357

  Fly   147 GCELAMMCDIIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGNMIGAQEAEKL 211
            |..:..:|||::|.:||.|..|...:...|....:....:::|.:.|.||...|..:.||||...
Mouse   358 GASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSR 422

  Fly   212 GLASKVVPADQLLGEAVKLGEKIGTHSNLIVQLCKEAVNTAYETTLQE 259
            ||.|:|........|.:...:::.:.|.::::..|..|.:..::.|:|
Mouse   423 GLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:304874	57/234 (24%)
Cdyl2	NP_083717.1	CHROMO	7..55	CDD:214605
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..177
		crotonase-like	249..445	CDD:119339	51/201 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810