Protein Alignment Echs1 and ECHDC1

DIOPT Version :10

• Sequence 1: NP_610910.1
• Gene: Echs1 / 36536
• FlyBaseID: FBgn0033879
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001132982.1
• Gene: ECHDC1 / 55862
• HGNCID: 21489
• Length: 307
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 66/262 - (25%)
• Similarity: 125/262 - (47%)
• Gaps: 28/262 - (10%)

  Fly    27 TRFSSSSTNNNW---EYIKT---------EVAGEGKNVGVITLNRPKALNALCNGLMKEL---ST 76
            |..|..||::.:   |..||         ::..|...:|::|||.|..:||....:|.:|   ..
Human    27 TGLSLYSTSHGFYEEEVKKTLQQFPGGSIDLQKEDNGIGILTLNNPSRMNAFSGVMMLQLLEKVI 91

  Fly    77 ALQQFSKDKTISAIVLTGSEKAFAAGADIK--EMVGNTYSQCIQGNFL-NDWTEVARTQKPIIAA 138
            .|:.:::.|   .:::.|::..|::|:|:.  :.:|..........|: |..|...|.....:|.
Human    92 ELENWTEGK---GLIVRGAKNTFSSGSDLNAVKSLGTPEDGMAVCMFMQNTLTRFMRLPLISVAL 153

  Fly   139 VNGYALGGGCELAMMCD--IIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGN 201
            |.|:|||||.|....||  ::....|.:|...|  :|.||..|||.||..::|..:|:::.....
Human   154 VQGWALGGGAEFTTACDFRLMTPESKIRFVHKE--MGIIPSWGGTTRLVEIIGSRQALKVLSGAL 216

  Fly   202 MIGAQEAEKLGLASKVVPAD---QLLGEAVKLGEKIGTHSNLIVQLCKEAVNTAYETTLQEGLKF 263
            .:.::.|..:|:..:|:.:.   :.|.||.:..::.......:::..|::|.:..|..|:|.|:.
Human   217 KLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEALQN 281

  Fly   264 ER 265
            ||
Human   282 ER 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:474030	62/252 (25%)
ECHDC1	NP_001132982.1	CaiD	61..300	CDD:440647	58/228 (25%)