Protein Alignment Echs1 and ECHDC2

DIOPT Version :10

• Sequence 1: NP_610910.1
• Gene: Echs1 / 36536
• FlyBaseID: FBgn0033879
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001185890.1
• Gene: ECHDC2 / 55268
• HGNCID: 23408
• Length: 292
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 103/297 - (34%)
• Similarity: 147/297 - (49%)
• Gaps: 19/297 - (6%)

  Fly    11 RAQCVLQAAARQPQVATRFSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKALNALCNGLMKELS 75
            |..|:|:  ..:|..|...:|.......|.....:||..:.:..|.:|||.|.|||.|..:.||.
Human     3 RVLCLLR--PWRPLRARGCASDGAAGGSEIQVRALAGPDQGITEILMNRPSARNALGNVFVSELL 65

  Fly    76 TALQQFSKDKTISAIVL-TGSEKAFAAGADIKEM-------VGNTYSQCIQGNFLNDWTEVARTQ 132
            ..|.|..:|:.:..::. :|.:..|.||||:||.       || .:.|.::| .:||   :|...
Human    66 ETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQMSEAEVG-VFVQRLRG-LMND---IAAFP 125

  Fly   133 KPIIAAVNGYALGGGCELAMMCDIIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMC 197
            .|.|||::|:|||||.|||:.||:..|...|..|..|...|.:|||||||||.|.:|.:.|.|:.
Human   126 APTIAAMDGFALGGGLELALACDLRVAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELI 190

  Fly   198 LTGNMIGAQEAEKLGLASKVV----PADQLLGEAVKLGEKIGTHSNLIVQLCKEAVNTAYETTLQ 258
            .||..:...||..|||.:..|    ..|.....|..|.::|...:.:.|:|.|.|::...|..:.
Human   191 FTGRRLSGTEAHVLGLVNHAVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIA 255

  Fly   259 EGLKFERRTFHATFSTADRKEGMTAFAEKRPAKFTNE 295
            .|:..|...:.....|.||.|||.||.|||..||..:
Human   256 SGMAIEGMCYAQNIPTRDRLEGMAAFREKRTPKFVGK 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:474030	97/268 (36%)
ECHDC2	NP_001185890.1	crotonase-like	38..292	CDD:474030	94/258 (36%)