DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Echs1 and echs1

DIOPT Version :9

Sequence 1:	NP_610910.1	Gene:	Echs1 / 36536	FlyBaseID:	FBgn0033879	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001004529.1	Gene:	echs1 / 368912	ZFINID:	ZDB-GENE-030616-617	Length:	291	Species:	Danio rerio

Alignment Length:	270	Identity:	175/270 - (64%)
Similarity:	206/270 - (76%)	Gaps:	2/270 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ATRFSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKALNALCNGLMKELSTALQQFSKDKTISAI 90
            |||.|||..  .:|||..:..||.||||.|.|||||||||||:|||.|:..||..|..|..:.||
Zfish    24 ATRQSSSGV--QYEYILVDKKGEKKNVGFIQLNRPKALNALCDGLMLEVGKALDAFEMDSEVGAI 86

  Fly    91 VLTGSEKAFAAGADIKEMVGNTYSQCIQGNFLNDWTEVARTQKPIIAAVNGYALGGGCELAMMCD 155
            |:||||||||||||||||...|:.:|..||||..|..|:..:||:||||||:|||||||.|||||
Zfish    87 VVTGSEKAFAAGADIKEMQNRTFQECYGGNFLAHWNRVSTVKKPVIAAVNGFALGGGCEFAMMCD 151

  Fly   156 IIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGNMIGAQEAEKLGLASKVVPA 220
            |||||:||:||||||.|||||||||||||||.||||.||||.|||:.|.||||::.||.||:.|.
Zfish   152 IIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQEAKQSGLVSKIFPV 216

  Fly   221 DQLLGEAVKLGEKIGTHSNLIVQLCKEAVNTAYETTLQEGLKFERRTFHATFSTADRKEGMTAFA 285
            |||:.||:|.||||..:|.|:..:.||:||.|:|.||.||.:||:|.|||||:|.||||||:||.
Zfish   217 DQLVPEAIKCGEKIAGNSKLVSAMAKESVNAAFELTLAEGSRFEKRLFHATFATEDRKEGMSAFV 281

  Fly   286 EKRPAKFTNE 295
            |||.|.|.::
Zfish   282 EKRKAAFQDK 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:304874	169/256 (66%)
echs1	NP_001004529.1	crotonase-like	34..291	CDD:304874	169/256 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595148
Domainoid	1	1.000	331	1.000	Domainoid score	I1129
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3018
Inparanoid	1	1.050	345	1.000	Inparanoid score	I2302
OMA	1	1.010	-	-		QHG61099
OrthoDB	1	1.010	-	-		D1221604at2759
OrthoFinder	1	1.000	-	-		FOG0003513
OrthoInspector	1	1.000	-	-		oto40766
orthoMCL	1	0.900	-	-		OOG6_101534
Panther	1	1.100	-	-	LDO	PTHR11941
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2501
SonicParanoid	1	1.000	-	-		X3958
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800