Protein Alignment Echs1 and HIBCH

DIOPT Version :9

• Sequence 1: NP_610910.1
• Gene: Echs1 / 36536
• FlyBaseID: FBgn0033879
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_055177.2
• Gene: HIBCH / 26275
• HGNCID: 4908
• Length: 386
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 83/346 - (23%)
• Similarity: 137/346 - (39%)
• Gaps: 91/346 - (26%)

  Fly    24 QVATRFSS-SSTNNNWEYIK--------TEVAGEGKN-VGVITLNRPKALNALCNGLMKELSTAL 78
            ::.:||:: ..||....:::        .||..|.|. .|||||||||.||||...:::::...|
Human     8 RLMSRFNAFKRTNTILHHLRMSKHTDAAEEVLLEKKGCTGVITLNRPKFLNALTLNMIRQIYPQL 72

  Fly    79 QQFSKDKTISAIVLTGS-EKAFAAGADI---------KEMVGNTYSQCIQGNFLNDWTEVARTQK 133
            :::.:|.....|::.|: .|||.||.||         |:.:...:.:  :...||:  .|...||
Human    73 KKWEQDPETFLIIIKGAGGKAFCAGGDIRVISEAEKAKQKIAPVFFR--EEYMLNN--AVGSCQK 133

  Fly   134 PIIAAVNGYALGGGCELAMMCDIIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCL 198
            |.:|.::|..:|||..|::......|.:|..|..||.|:|..|..||...|.|:.|| ....:.|
Human   134 PYVALIHGITMGGGVGLSVHGQFRVATEKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLAL 197

  Fly   199 TGNMIGAQEAEKLGLASKVVPADQL--------------------LGEAVKLGEKIGTHSNLIVQ 243
            ||..:..::..:.|:|:..|.:::|                    :.|......||....:.|::
Human   198 TGFRLKGRDVYRAGIATHFVDSEKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILE 262

  Fly   244 LCKEAVNTAYET----------------------------------------------TLQEGLK 262
            ...:.:|:.:..                                              ||||.|.
Human   263 EHMDKINSCFSANTVEEIIENLQQDGSSFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLT 327

  Fly   263 FERRTFHATFSTADRKEGMTA 283
            .|.|...|.....|..||:.|
Human   328 MEYRLSQACMRGHDFHEGVRA 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:304874	79/332 (24%)
HIBCH	NP_055177.2	PRK05617	34..378	CDD:235533	79/320 (25%)
		ECH_2	47..375	CDD:292731	75/307 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810