Protein Alignment Echs1 and ECHS1

DIOPT Version :10

• Sequence 1: NP_610910.1
• Gene: Echs1 / 36536
• FlyBaseID: FBgn0033879
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 159/282 - (56%)
• Similarity: 205/282 - (72%)
• Gaps: 1/282 - (0%)

  Fly    14 CVLQAAARQPQVATRFSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKALNALCNGLMKELSTAL 78
            || :...|.|.....:...::..|:|||..|..|:...||:|.|||||||||||:||:.||:.||
Human    10 CV-RGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQAL 73

  Fly    79 QQFSKDKTISAIVLTGSEKAFAAGADIKEMVGNTYSQCIQGNFLNDWTEVARTQKPIIAAVNGYA 143
            :.|.:|..:.||||||.:||||||||||||...::..|....||..|..:.:.:||:||||||||
Human    74 KTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYA 138

  Fly   144 LGGGCELAMMCDIIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGNMIGAQEA 208
            .||||||||||||||||:||:|.||||.:||||||||||||||.||||.||||.|||:.|.||:|
Human   139 FGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203

  Fly   209 EKLGLASKVVPADQLLGEAVKLGEKIGTHSNLIVQLCKEAVNTAYETTLQEGLKFERRTFHATFS 273
            ::.||.||:.|.:.|:.||::..|||.::|.::|.:.||:||.|:|.||.||.|.|::.|::||:
Human   204 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFA 268

  Fly   274 TADRKEGMTAFAEKRPAKFTNE 295
            |.|||||||||.|||.|.|.::
Human   269 TDDRKEGMTAFVEKRKANFKDQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:474030	155/256 (61%)
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	154/255 (60%)