DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Echs1 and ech-1.1

DIOPT Version :9

Sequence 1:	NP_610910.1	Gene:	Echs1 / 36536	FlyBaseID:	FBgn0033879	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_506810.1	Gene:	ech-1.1 / 180037	WormBaseID:	WBGene00001150	Length:	755	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	80/281 - (28%)
Similarity:	132/281 - (46%)	Gaps:	34/281 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKAL-NALCNGLMKELSTALQQFSKDKTISAI-V 91
            |:..||:      :.|..|:   |.|:.::.|... |.|...|..|::..|.:...|:::.|| |
Worm    27 FAVHSTH------RVEKQGD---VAVMKIDLPNTTENVLNKALFAEMNETLDRLQSDQSVKAIVV 82

  Fly    92 LTGSEKAFAAGADIKEMVGNTYSQCIQGNFLNDWTE----VARTQKPIIAAVNGYALGGGCELAM 152
            ::|...:|.|||||:.......:..: .|.|.:..:    :..:||||:||:.|..:|||.|:|:
Worm    83 MSGKPNSFVAGADIQMFKAEKTAAGV-SNLLREGQKQLLTIELSQKPIVAAIMGSCMGGGLEIAL 146

  Fly   153 MCD--IIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGNMIGAQEAEKLGLAS 215
            .|.  |.....|...|.||:.||.:||.||||||.::......:::.|||..|.|.:|.|:|:..
Worm   147 ACHYRIAVNDKKTLLGLPEVTLGIMPGDGGTQRLPKLTTVQNVLDLTLTGKRIKANKAMKIGIVD 211

  Fly   216 KVVPADQLLGEAVKLGEKIGTH---SNLIVQLCKEAVNTAYETTLQEGLKFERRTFHATFSTADR 277
            :|:   |.||:.:....:. ||   ..:.||..:|..|...:....:|.     ..:||.:....
Worm   212 RVI---QPLGDGICTSTET-THKYLEEIAVQSARELANGKLKINRDKGF-----VHNATQAVMTS 267

  Fly   278 K----EGMTAFAEKRPAKFTN 294
            |    ..:...|:.:..|.||
Worm   268 KFVLDNVILKMAKNKLIKLTN 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:304874	75/271 (28%)
ech-1.1	NP_506810.1	fa_ox_alpha_mit	20..754	CDD:131494	80/281 (28%)
		crotonase-like	34..216	CDD:119339	60/188 (32%)
		3HCDH_N	355..533	CDD:280833
		3HCDH	535..630	CDD:279114
		3HCDH	668..754	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810