DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Echs1 and ech-8

DIOPT Version :9

Sequence 1:	NP_610910.1	Gene:	Echs1 / 36536	FlyBaseID:	FBgn0033879	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_501876.2	Gene:	ech-8 / 177905	WormBaseID:	WBGene00001157	Length:	437	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	48/225 - (21%)
Similarity:	75/225 - (33%)	Gaps:	54/225 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VATRFSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKALNALCNGLMKELSTALQ---QFSKDKT 86
            :|..|..|........:..:.|...||...||..|.||...|.:..:::|...||   .|.|...
Worm    54 IAIAFCLSGFETYLVEVNNKAAEFCKNELEITYKREKAFRRLNDSKVEKLRKNLQITTDFQKLNN 118

  Fly    87 ISAIVLTGSEKAFAAGADIKEMVGN----TYSQCIQGN-----FLNDWTEVARTQKPIIAAVNGY 142
            ...||    |..|......||:...    ....||.|.     .||:.:.|.|....::    |.
Worm   119 CDLIV----EAVFEDMKLKKELFTKLDKICKPSCIFGTNTSSLDLNEMSSVLRDPTKVV----GI 175

  Fly   143 ALGGGCELAMMCDIIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGNMIGAQE 207
            .......|..|.::||                     |::..::.|  :.|.|.|        :.
Worm   176 HFFNPANLIRMVEVIY---------------------GSKTSSKAV--ATAFEAC--------RS 209

  Fly   208 AEKLGLASKVVPA---DQLLGEAVKLGEKI 234
            .:||.:.....||   ::|||..:...:|:
Worm   210 IKKLPVLVGNCPAFVFNRLLGVYLNQSQKL 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:304874	45/213 (21%)
ech-8	NP_501876.2	FadB	38..312	CDD:224170	48/225 (21%)
		3HCDH_N	41..220	CDD:280833	42/204 (21%)
		3HCDH	223..310	CDD:279114	4/17 (24%)
		3HCDH	347..>391	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810