Protein Alignment Echs1 and Cdyl

DIOPT Version :10

• Sequence 1: NP_610910.1
• Gene: Echs1 / 36536
• FlyBaseID: FBgn0033879
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_034011.1
• Gene: Cdyl / 12593
• MGIID: 1339956
• Length: 593
• Species: Mus musculus
• Alignment Length: 274
• Identity: 64/274 - (23%)
• Similarity: 124/274 - (45%)
• Gaps: 13/274 - (4%)

  Fly    28 RFSSSSTNNNWEYIKTEVAGEGKNVGVITLNRPKALNALCNGLMKELSTALQQFSKDKTISAIVL 92
            |||...|.:.:.|....|..:.....::...:....|:|...:|||:.:||...:.|.: ..::|
Mouse   324 RFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDS-KLVLL 387

  Fly    93 TGSEKAFAAGAD----IKEMVGNTYSQCIQ-----GNFLNDWTEVARTQKPIIAAVNGYALGGGC 148
            :.....|..|.|    |:.:..:...:..:     .||:|.:.:.   :||||.||||.|:|.|.
Mouse   388 SAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIRNFVNTFIQF---KKPIIVAVNGPAIGLGA 449

  Fly   149 ELAMMCDIIYAGDKAKFGQPEIALGTIPGAGGTQRLTRVVGKSKAMEMCLTGNMIGAQEAEKLGL 213
            .:..:||:::|.:||.|..|....|..|....|....:::|.:.|.||..:|..:.||||...||
Mouse   450 SILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGL 514

  Fly   214 ASKVVPADQLLGEAVKLGEKIGTHSNLIVQLCKEAVNTAYETTLQEGLKFERRTFHATFSTADRK 278
            .|:|........|.:...:::.:.:.::::..|..|....:..|::..:.|.......:.:|...
Mouse   515 VSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGM 579

  Fly   279 EGMTAFAEKRPAKF 292
            :.|..:.:::..:|
Mouse   580 DSMLKYLQRKIDEF 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Echs1	NP_610910.1	crotonase-like	37..294	CDD:474030	60/265 (23%)
Cdyl	NP_034011.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30
		Interaction with EZH2. /evidence=ECO:0000250|UniProtKB:Q9Y232	56..304
		CD_CDY	57..106	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..158
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..223
		crotonase-like	339..535	CDD:119339	52/199 (26%)
		Acetyl-CoA-binding domain. /evidence=ECO:0000255	357..589		57/235 (24%)