DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syngr and syngr2b

DIOPT Version :9

Sequence 1:	NP_610908.1	Gene:	Syngr / 36533	FlyBaseID:	FBgn0033876	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001076327.1	Gene:	syngr2b / 568509	ZFINID:	ZDB-GENE-070424-19	Length:	235	Species:	Danio rerio

Alignment Length:	238	Identity:	80/238 - (33%)
Similarity:	115/238 - (48%)	Gaps:	20/238 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEK--DGKEYCLYNGDGMACK 77
            |||...||..||.:.|..:||.|:|.|.|:|::|||..|::||:...  :.:..|::|.:..||.
Zfish     7 AYGASLAGAGFDLVKFIKQPQTVVRFLSWVFAIVVFSSITAEGYVNSTDEAEVRCVFNRNDGACH 71

  Fly    78 YGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSA 142
            ||..:||..|||.:||:..:.:...:|:.:.||..||||:.||..|||::||.|.....|||.::
Zfish    72 YGVGIGVIAFLACVGFLLADAILPLISNAQERKYIVMADLAFSGCWTFLWFVCFCLTADQWSKTS 136

  Fly   143 PPPLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDP--------ANVVH 199
            ... ||...::...|.|..|||.||......|..||..|. :|.|.:: |||        .:...
Zfish   137 DRS-GIPTDAVHAVIAFSFFSIASWGALTYFAVVRFRQGV-EEVTQSY-TDPPPDLSSPYPSTYT 198

  Fly   200 QQAYGYSMDNDNDQYSASPF-GQPQQGGMEQQQSGMEYQQPTY 241
            ...|....:...|.|...|| ..|...|.      ..:|.|.|
Zfish   199 PPTYPSFQNTGADIYQQPPFTPNPDPSGQ------TSFQPPVY 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syngr	NP_610908.1	MARVEL	34..169	CDD:307448	53/136 (39%)
syngr2b	NP_001076327.1	MARVEL	22..166	CDD:279608	54/144 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593612
Domainoid	1	1.000	124	1.000	Domainoid score	I5443
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45451
OrthoDB	1	1.010	-	-		D1549362at2759
OrthoFinder	1	1.000	-	-		FOG0001420
OrthoInspector	1	1.000	-	-		otm25361
orthoMCL	1	0.900	-	-		OOG6_104437
Panther	1	1.100	-	-	O	PTHR10838
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X989
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.860