DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syngr and syngr1a

DIOPT Version :9

Sequence 1:	NP_610908.1	Gene:	Syngr / 36533	FlyBaseID:	FBgn0033876	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_001006067.1	Gene:	syngr1a / 450047	ZFINID:	ZDB-GENE-041010-169	Length:	223	Species:	Danio rerio

Alignment Length:	240	Identity:	87/240 - (36%)
Similarity:	128/240 - (53%)	Gaps:	33/240 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWTEK--DGKEYCLYNGDGMACK 77
            |||.|||||.|||:||..:||.::|.:.|:||:|:||||::||:..:  :.:|:|::|.:..||.
Zfish     4 AYGAGKAGGTFDPITFFQQPQTILRIVSWIFSIVIFGCIANEGYVNRPDEVEEFCIFNRNQNACN 68

  Fly    78 YGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSSA 142
            |...:|...||....|:..:..|.::||||.||:.|:||:|.||.|:|::||.|.:|.:||..:.
Zfish    69 YAVGMGALDFLCCAAFLALDIYFPQISSVKDRKKAVLADIGVSAFWSFVWFVGFCFLANQWQVAN 133

  Fly   143 PP--PLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQAYGY 205
            |.  ||..||.:.:.||.|..|||.:||..|...::|:.:|:.....|...|||
Zfish   134 PEDNPLKEGADAARAAITFAFFSIFTWAGQAFFGFQRYKLGSSSSLFSQDYTDP----------- 187

  Fly   206 SMDNDNDQYSASPFGQPQQG--------GMEQQQSGM-EYQQPTY 241
                     |..|...|.:|        .||....|. .||...|
Zfish   188 ---------SQDPAAAPSEGTEYTGYNADMEANYDGSGGYQNQDY 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syngr	NP_610908.1	MARVEL	34..169	CDD:307448	56/138 (41%)
syngr1a	NP_001006067.1	MARVEL	19..166	CDD:279608	59/146 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593609
Domainoid	1	1.000	124	1.000	Domainoid score	I5443
eggNOG	1	0.900	-	-		E1_KOG4016
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3456
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4175
OMA	1	1.010	-	-		QHG45451
OrthoDB	1	1.010	-	-		D1549362at2759
OrthoFinder	1	1.000	-	-		FOG0001420
OrthoInspector	1	1.000	-	-		otm25361
orthoMCL	1	0.900	-	-		OOG6_104437
Panther	1	1.100	-	-	O	PTHR10838
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2805
SonicParanoid	1	1.000	-	-		X989
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800