DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syngr and Syngr2

DIOPT Version :9

Sequence 1:	NP_610908.1	Gene:	Syngr / 36533	FlyBaseID:	FBgn0033876	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_033330.1	Gene:	Syngr2 / 20973	MGIID:	1328324	Length:	224	Species:	Mus musculus

Alignment Length:	231	Identity:	87/231 - (37%)
Similarity:	129/231 - (55%)	Gaps:	18/231 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGWT--EKDGKEYCLYNGDGMAC 76
            ||||...|||:||...|..:||||.|.:..:.:::||.||..||:|  ....:.||::|.:..||
Mouse     4 GAYGAANAGGSFDLRRFLSQPQVVTRLVSMVLALIVFSCIFGEGYTNIHTSDQLYCVFNQNEDAC 68

  Fly    77 KYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSSS 141
            :||:.:||..||||..|:..:..|.::|:...||..|:.|:.|||||||::||.|.:|.:||:::
Mouse    69 RYGSAIGVLAFLASAFFLVVDAFFSQISNATDRKYLVIGDLLFSALWTFLWFVGFCFLTNQWAAT 133

  Fly   142 APPPLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPA---NVVHQQAY 203
            .|..:.:||.|.:.||.|..|||.||.:.|.:||:|:..|. |.|...: .||.   |..:....
Mouse   134 KPQDVRVGADSARAAITFSFFSIFSWGVLASLAYQRYKAGV-DAFIQNY-VDPTPDPNTAYASYP 196

  Fly   204 GYSMDNDNDQYSASPFGQPQQGGMEQQQSGMEYQQP 239
            ..|::|    |...||.|    .:|..:.   ||.|
Mouse   197 SASVEN----YQQPPFTQ----NVETTEG---YQPP 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syngr	NP_610908.1	MARVEL	34..169	CDD:307448	57/136 (42%)
Syngr2	NP_033330.1	MARVEL	20..165	CDD:307448	59/144 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848205
Domainoid	1	1.000	121	1.000	Domainoid score	I5675
eggNOG	1	0.900	-	-		E1_KOG4016
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4169
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45451
OrthoDB	1	1.010	-	-		D1549362at2759
OrthoFinder	1	1.000	-	-		FOG0001420
OrthoInspector	1	1.000	-	-		otm42818
orthoMCL	1	0.900	-	-		OOG6_104437
Panther	1	1.100	-	-	LDO	PTHR10838
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X989
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.770