DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Syngr and Syngr1

DIOPT Version :9

Sequence 1:	NP_610908.1	Gene:	Syngr / 36533	FlyBaseID:	FBgn0033876	Length:	241	Species:	Drosophila melanogaster
Sequence 2:	NP_997591.1	Gene:	Syngr1 / 20972	MGIID:	1328323	Length:	234	Species:	Mus musculus

Alignment Length:	235	Identity:	91/235 - (38%)
Similarity:	131/235 - (55%)	Gaps:	27/235 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 GGAYGGGKAGGAFDPLTFAMKPQVVIRALCWLFSVVVFGCISSEGW--TEKDGKEYCLYNGDGMA 75
            |||||.|||||||||.|...:|..::|.:.|:||:||||.|.:||:  ..::.:|:|:||.:..|
Mouse     3 GGAYGAGKAGGAFDPYTLVRQPHTILRVVSWVFSIVVFGSIVNEGYLNNPEEEEEFCIYNRNPNA 67

  Fly    76 CKYGNMVGVFGFLASMGFMGGEFLFERMSSVKSRKRYVMADMGFSALWTFMYFVAFLYLWSQWSS 140
            |.||..|||..||..:.::..:..|.::||||.||:.|::|:|.||.|.|.:||.|.:|.:||..
Mouse    68 CSYGVTVGVLAFLTCLLYLALDVYFPQISSVKDRKKAVLSDIGVSAFWAFFWFVGFCFLANQWQV 132

  Fly   141 SAPP--PLGIGAGSMKTAIWFCLFSIVSWALCALMAYKRFLIGAGDEFTSAFETDPANVVHQQAY 203
            |.|.  ||..|..:.:.||.|..|||.:||..|::|::|:.|||.....|....||
Mouse   133 SKPKDNPLNEGTDAARAAIAFSFFSIFTWAGQAVLAFQRYQIGADSALFSQDYMDP--------- 188

  Fly   204 GYSMDNDNDQYSASPFGQPQQG----GMEQQQSGMEYQQP 239
                 :.:.....:|:.:|..|    ||     |..||.|
Mouse   189 -----SQDSSMPYAPYVEPSAGSDPAGM-----GGTYQHP 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syngr	NP_610908.1	MARVEL	34..169	CDD:307448	57/138 (41%)
Syngr1	NP_997591.1	MARVEL	21..167	CDD:366555	59/145 (41%)
Syngr1	NP_997591.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..234		8/23 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848208
Domainoid	1	1.000	121	1.000	Domainoid score	I5675
eggNOG	1	0.900	-	-		E1_KOG4016
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3456
Inparanoid	1	1.050	166	1.000	Inparanoid score	I4169
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45451
OrthoDB	1	1.010	-	-		D1549362at2759
OrthoFinder	1	1.000	-	-		FOG0001420
OrthoInspector	1	1.000	-	-		otm42818
orthoMCL	1	0.900	-	-		OOG6_104437
Panther	1	1.100	-	-	O	PTHR10838
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2805
SonicParanoid	1	1.000	-	-		X989
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800