DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG6357 and CTSF

DIOPT Version :9

Sequence 1:NP_610907.1 Gene:CG6357 / 36532 FlyBaseID:FBgn0033875 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_003784.2 Gene:CTSF / 8722 HGNCID:2531 Length:484 Species:Homo sapiens


Alignment Length:265 Identity:54/265 - (20%)
Similarity:94/265 - (35%) Gaps:83/265 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   219 IEERSSPAPEIRKEEATTSTSEIDND------NIICQPAWEKFLIDFKPSYQDDTETEKRRNVFC 277
            |...|...|:.|.|..::..|.::.|      .:.....::.|:|.:..:|:...|...|.:||.
Human   148 ISSLSQNHPDNRNETFSSVISLLNEDPLSQDLPVKMASIFKNFVITYNRTYESKEEARWRLSVFV 212

  Fly   278 DNFKSIHKHNVQ-FDLGNISFKKGINQWSDLTVEEWK-------------NKQRPAFN------P 322
            :|.  :....:| .|.|...:  |:.::||||.||::             ||.:.|.:      |
Human   213 NNM--VRAQKIQALDRGTAQY--GVTKFSDLTEEEFRTIYLNTLLRKEPGNKMKQAKSVGDLAPP 273

  Fly   323 EF---SKVEATTKISKDKRDDNTCQAAWK---------KFLIDFGAKYQDEKETEKRRTIFCDN- 374
            |:   || .|.||:    :|...|.:.|.         ::.::.|...    ...::..:.||. 
Human   274 EWDWRSK-GAVTKV----KDQGMCGSCWAFSVTGNVEGQWFLNQGTLL----SLSEQELLDCDKM 329

  Fly   375 ------------WKAI--------------QEHNEQFELGVESFKKGINQWSDLTVEE-----WK 408
                        :.||              |.|.:......|..|..||...:|:..|     |.
Human   330 DKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQSCNFSAEKAKVYINDSVELSQNEQKLAAWL 394

  Fly   409 TKQRP 413
            .|:.|
Human   395 AKRGP 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6357NP_610907.1 Inhibitor_I29 72..132 CDD:285458
Inhibitor_I29 162..221 CDD:214853 1/1 (100%)
Inhibitor_I29 252..311 CDD:214853 16/59 (27%)
Inhibitor_I29 347..406 CDD:214853 13/94 (14%)
CTSFNP_003784.2 Inhibitor_I29 187..243 CDD:214853 16/59 (27%)
Peptidase_C1 271..482 CDD:278538 26/138 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.