DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6357 and si:dkey-228a15.1

DIOPT Version :9

Sequence 1:	NP_610907.1	Gene:	CG6357 / 36532	FlyBaseID:	FBgn0033875	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	XP_017207744.1	Gene:	si:dkey-228a15.1 / 564472	ZFINID:	ZDB-GENE-060503-344	Length:	313	Species:	Danio rerio

Alignment Length:	332	Identity:	67/332 - (20%)
Similarity:	119/332 - (35%)	Gaps:	88/332 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SPATQKINPEIGVTTGKSDADSSTPTIEHTSGLSEFEEECQF-AWQRFLVDFDVHYDN-DYERQK 91
            :||..:..|:.|          ....::....|..:|.|..| ||    .||:.:... ||....
Zfish    25 NPAGNRTVPDFG----------KMYYVKGVISLPSYEIEEPFEAW----YDFEGNRSRIDYYNGT 75

  Fly    92 RRDIFCENWQKVRDHNLKYDLGVVSFKKGINQWSDL-TFEEWKEKQTP----KVMPEIAS-ESSK 150
            .|.....|         ..|.|.:...|.:...||: .|:....|:.|    ..||::.. |..|
Zfish    76 TRTFLIGN---------DLDYGAIYQIKPVLPPSDIKCFQLKGTKEEPIRPQSAMPDVQGFEFEK 131

  Fly   151 EERDKVNCQAAWEKFLIDFGAQ---YKNANETEKRRNVF--------------------CANWRA 192
            .|    :|:          |||   :|...|...::|.:                    ...:..
Zfish   132 ME----DCK----------GAQCEVWKTITEAGHKKNTYRLWVTRPEGNDAPATPHRFEMEGFNT 182

  Fly   193 IVE-HN----VQYEKWAEPFKRDI-NQWTDHTIEERSSPAPEIRKEEAT-----TSTSEIDNDNI 246
            ::: ||    ::|..::...:.|: ......|.||...| ||..:..|.     .||:.:.:.:.
Zfish   183 LLDSHNDKYSIEYSDFSSQTEPDVFTPPAGFTCEEFPDP-PEQHQILANPIQDYVSTNPVSHAHR 246

  Fly   247 ICQPAWEKFLIDFKPSYQDDTETEKRRNVFCDNFKSIHKHNVQFDLGNISFKKGINQWSDLTVEE 311
            :..|..||    |...|:.:.|.::|...|..:|:.::..|.:    .:||..|||:.:|.:..|
Zfish   247 MFGPFKEK----FNRQYKSEEEHQEREINFVQSFRFVNSTNRK----GLSFTVGINKRADWSRAE 303

  Fly   312 WKNKQRP 318
            .:..:.|
Zfish   304 TRKSKIP 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458	13/61 (21%)
		Inhibitor_I29	162..221	CDD:214853	11/87 (13%)
		Inhibitor_I29	252..311	CDD:214853	15/58 (26%)
		Inhibitor_I29	347..406	CDD:214853
si:dkey-228a15.1	XP_017207744.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900