DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6357 and Ctsql2

DIOPT Version :9

Sequence 1:	NP_610907.1	Gene:	CG6357 / 36532	FlyBaseID:	FBgn0033875	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001002813.2	Gene:	Ctsql2 / 408201	RGDID:	1303225	Length:	343	Species:	Rattus norvegicus

Alignment Length:	166	Identity:	38/166 - (22%)
Similarity:	67/166 - (40%)	Gaps:	46/166 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 SGLSEFEEECQFAWQRFLVDFDVHYDNDYERQKRRDIFCENWQKVRDHNLKYDLGVVSFKKGINQ 123
            ||.|.|.......||.:.:.::..|..:.|..| |.::.||.:|:..||.:..||..::...||.
  Rat    16 SGASAFNLSLDVQWQEWKMKYEKLYSPEEELLK-RVVWEENVKKIELHNRENSLGKNTYIMEINN 79

  Fly   124 WSDLTFEEWKEKQTPKVMPEIASESSKEERDKVN--CQAAWEKFLIDFGAQYKNANETEKRRNVF 186
            ::|||.||:|:..|...:|             :|  .::.|::.|   |:.:.|:
  Rat    80 FADLTDEEFKDMITGITLP-------------INNTMKSLWKRAL---GSPFPNS---------- 118

  Fly   187 CANWRAIVEHNVQYEK----------------WAEP 206
             ..||..:..::.:.|                ||.|
  Rat   119 -WYWRDALPKSIDWRKEGYVTRVREQGKCKSCWAFP 153

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458	19/59 (32%)
		Inhibitor_I29	162..221	CDD:214853	10/61 (16%)
		Inhibitor_I29	252..311	CDD:214853
		Inhibitor_I29	347..406	CDD:214853
Ctsql2	NP_001002813.2	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
Ctsql2	NP_001002813.2	Peptidase_C1	125..342	CDD:278538	4/29 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12411
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910