DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6357 and Ctsf

DIOPT Version :9

Sequence 1:	NP_610907.1	Gene:	CG6357 / 36532	FlyBaseID:	FBgn0033875	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001029282.1	Gene:	Ctsf / 361704	RGDID:	1308181	Length:	462	Species:	Rattus norvegicus

Alignment Length:	196	Identity:	44/196 - (22%)
Similarity:	72/196 - (36%)	Gaps:	46/196 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SPATQKINPEIGVTTGKSDADSSTPTIEHTSGLSEFEEECQFAWQRFLVDFDVHYDNDYERQKRR 93
            ||...|:     ..:|.....:..|.::......:|..:....::.|:..::..|::..|.|.|.
  Rat   127 SPVNAKV-----TESGNETFRAFLPMLDKDPLPQDFSVKMATLFKDFMTTYNRTYESREEAQWRL 186

  Fly    94 DIFCENW---QKVRDHNLKYDLGVVSFKKGINQWSDLTFEEWKEKQTPKVMPEIASES------S 149
            .:|..|.   ||::    ..|.|...:  ||.::||||.||:   .|..:.|.:..||      :
  Rat   187 TVFARNMIRAQKIQ----ALDRGTAQY--GITKFSDLTEEEF---HTIYLNPLLQKESGGKMSLA 242

  Fly   150 KEERDKVNCQAAWEKFLIDFGAQYKNANETEKRRNVFCAN-WRAIVEHNVQYEKWAEPFKRDINQ 213
            |...|....:..|.|         |.| .||.:....|.: |...|..||:            .|
  Rat   243 KSINDLAPPEWDWRK---------KGA-VTEVKDQGMCGSCWAFSVTGNVE------------GQ 285

  Fly   214 W 214
            |
  Rat   286 W 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458	18/62 (29%)
		Inhibitor_I29	162..221	CDD:214853	13/54 (24%)
		Inhibitor_I29	252..311	CDD:214853
		Inhibitor_I29	347..406	CDD:214853
Ctsf	NP_001029282.1	Inhibitor_I29	165..221	CDD:214853	17/61 (28%)
Ctsf	NP_001029282.1	Peptidase_C1	249..460	CDD:395062	13/60 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900