DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6357 and Ctsc

DIOPT Version :9

Sequence 1:	NP_610907.1	Gene:	CG6357 / 36532	FlyBaseID:	FBgn0033875	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_058793.1	Gene:	Ctsc / 25423	RGDID:	2445	Length:	462	Species:	Rattus norvegicus

Alignment Length:	200	Identity:	40/200 - (20%)
Similarity:	62/200 - (31%)	Gaps:	85/200 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LGVPLLLYLMGVALGVPVSTSSPATQKINP-------EIGVTTGKSDADSST--PTIE----HTS 59
            |...|||.|:||.   .||:.:||......       ::|....:|..:.|.  ||.|    |..
  Rat     8 LRAALLLVLLGVC---TVSSDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLK 69

  Fly    60 GLSEFEEEC-------------------QFAWQRFLVDFDVHYDNDYERQKRR------------ 93
            .|....:|.                   .:.|..|.         .||.:..|
  Rat    70 KLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFF---------KYEVKGSRAISYCHETMTGW 125

  Fly    94 --DIFCENW-----QKVRDHNLKYDLGVV------------------SFKKGIN----QWSDLTF 129
              |:...||     :|:.:|:.|..:.|.                  :|.|.||    .|:..|:
  Rat   126 VHDVLGRNWACFVGKKMANHSEKVYVNVAHLGGLQEKYSERLYSHNHNFVKAINSVQKSWTATTY 190

  Fly   130 EEWKE 134
            ||:::
  Rat   191 EEYEK 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458	19/100 (19%)
		Inhibitor_I29	162..221	CDD:214853
		Inhibitor_I29	252..311	CDD:214853
		Inhibitor_I29	347..406	CDD:214853
Ctsc	NP_058793.1	CathepsinC_exc	25..138	CDD:400909	19/121 (16%)
		Pox_I6	168..>204	CDD:333259	8/27 (30%)
		Peptidase_C1A_CathepsinC	230..459	CDD:239112
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900