DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG6357 and CTSZ

DIOPT Version :9

Sequence 1:NP_610907.1 Gene:CG6357 / 36532 FlyBaseID:FBgn0033875 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_001327.2 Gene:CTSZ / 1522 HGNCID:2547 Length:303 Species:Homo sapiens


Alignment Length:125 Identity:28/125 - (22%)
Similarity:44/125 - (35%) Gaps:36/125 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 RNVFCANWRAIV--EHNVQY--EKWAEPFKRDINQWTDHTIEERSSPAPEIRKEEATTSTSEIDN 243
            |||...|:.:|.  :|..||  ..||            |......:....|:::.|..||. :..
Human    69 RNVDGVNYASITRNQHIPQYCGSCWA------------HASTSAMADRINIKRKGAWPSTL-LSV 120

  Fly   244 DNII-------CQPAWEKFLIDFK----------PSYQ-DDTETEKRRNV-FCDNFKSIH 284
            .|:|       |:...:..:.|:.          .:|| .|.|.:|.... .|:.||..|
Human   121 QNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQECDKFNQCGTCNEFKECH 180

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG6357NP_610907.1 Inhibitor_I29 72..132 CDD:285458
Inhibitor_I29 162..221 CDD:214853 11/41 (27%)
Inhibitor_I29 252..311 CDD:214853 10/45 (22%)
Inhibitor_I29 347..406 CDD:214853
CTSZNP_001327.2 Peptidase_C1A_CathepsinX 62..302 CDD:239149 28/125 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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