Protein Alignment CG6357 and CTSO

DIOPT Version :9

• Sequence 1: NP_610907.1
• Gene: CG6357 / 36532
• FlyBaseID: FBgn0033875
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_001325.1
• Gene: CTSO / 1519
• HGNCID: 2542
• Length: 321
• Species: Homo sapiens
• Alignment Length: 199
• Identity: 42/199 - (21%)
• Similarity: 70/199 - (35%)
• Gaps: 55/199 - (27%)

  Fly   259 FKPSYQDDTETEKRRNVFCDNFK-SIHKH---NVQFDLGNISFKKGINQWSDLTVEEWKN---KQ 316
            |.|::....|.|...      |: |:::|   |..|...|.:...||||:|.|..||:|.   :.
Human    29 FTPTWPRSREREAAA------FRESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLRS 87

  Fly   317 RPAFNPEFSKVEATTKIS----------KDK------RDDNTCQAAWKKFLIDFGAKYQDEKETE 365
            :|:..|.:| .|....|.          :||      |:...|...|...::  ||.
Human    88 KPSKFPRYS-AEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVV--GAV-------- 141

  Fly   366 KRRTIFCDNWKAIQEHNEQFELGVESFKKGINQWSDLTVEEWKTKQRPNLAPEFSKEETTTKISK 430
              .:.:....|.:::.:.|..:.......|.|..|.|....|..|.:             .|:.|
Human   142 --ESAYAIKGKPLEDLSVQQVIDCSYNNYGCNGGSTLNALNWLNKMQ-------------VKLVK 191

  Fly   431 EKKY 434
            :.:|
Human   192 DSEY 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458
		Inhibitor_I29	162..221	CDD:214853
		Inhibitor_I29	252..311	CDD:214853	16/55 (29%)
		Inhibitor_I29	347..406	CDD:214853	9/58 (16%)
CTSO	NP_001325.1	Peptidase_C1A	109..319	CDD:239068	18/112 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900