DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6357 and Ctsw

DIOPT Version :9

Sequence 1:	NP_610907.1	Gene:	CG6357 / 36532	FlyBaseID:	FBgn0033875	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_034115.2	Gene:	Ctsw / 13041	MGIID:	1338045	Length:	371	Species:	Mus musculus

Alignment Length:	184	Identity:	39/184 - (21%)
Similarity:	66/184 - (35%)	Gaps:	46/184 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 TDHTIEERSSPAPEIRKEEATTSTSEIDNDNIICQPAWEKFLIDFKPSYQDDTETEKRRNVFCDN 279
            :|..:.:.:.|.|...||                  .::.|.|.|..||.:..|..:|.::|..|
Mouse    21 SDSLLTKDAGPRPLELKE------------------VFKLFQIRFNRSYWNPAEYTRRLSIFAHN 67

  Fly   280 FKSIHKHNVQFDLGNISFKKGINQWSDLTVEE----WKNKQRPAFNPEFS-KVEATT-------- 331
            .....:.. |.|||...|  |...:||||.||    :..::.|...|..: |||:.|
Mouse    68 LAQAQRLQ-QEDLGTAEF--GETPFSDLTEEEFGQLYGQERSPERTPNMTKKVESNTWGESVPRT 129

  Fly   332 -------KISKDKRDDNTCQAAWKKFLID-----FGAKYQDEKETEKRRTIFCD 373
                   .|....::..:|:..|.....|     :..|:|...:...:..:.|:
Mouse   130 CDWRKAKNIISSVKNQGSCKCCWAMAAADNIQALWRIKHQQFVDVSVQELLDCE 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6357	NP_610907.1	Inhibitor_I29	72..132	CDD:285458
		Inhibitor_I29	162..221	CDD:214853	1/5 (20%)
		Inhibitor_I29	252..311	CDD:214853	19/58 (33%)
		Inhibitor_I29	347..406	CDD:214853	5/32 (16%)
Ctsw	NP_034115.2	Inhibitor_I29	40..96	CDD:214853	19/58 (33%)
Ctsw	NP_034115.2	Peptidase_C1	126..356	CDD:278538	7/58 (12%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900