DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and RD21B

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_568620.1	Gene:	RD21B / 834321	AraportID:	AT5G43060	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	376	Identity:	127/376 - (33%)
Similarity:	190/376 - (50%)	Gaps:	66/376 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 MTLGLALLGAVSLQQLQSFPKLCDVQNFDD---FLRQTGKVYSDEERVY---------------- 56
            |.|.||::|.       |:.....:.::|:   ...:|.:..|:.||:|
plant     9 MILLLAMIGV-------SYAMDMSIISYDENHHITTETSRSDSEVERIYEAWMVEHGKKKMNQNG 66

  Fly    57 -------RESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATL-LGSK----ISEFG 109
                   |..||  |.:|..:...|..|  ..::||:...||:|.:|..:: ||:|    :.:..
plant    67 LGAEKDQRFEIF--KDNLRFIDEHNTKN--LSYKLGLTRFADLTNEEYRSMYLGAKPTKRVLKTS 127

  Fly   110 ERYTNGHINFVTARNPASANLPEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGV 174
            :||        .||  ....||:..|||::|.|.....|| .||:||:|:|.||:||.....||.
plant   128 DRY--------QAR--VGDALPDSVDWRKEGAVADVKDQG-SCGSCWAFSTIGAVEGINKIVTGD 181

  Fly   175 LASLSQQNLVDCADDYGNMGCDGGFQEYGFEY-IRDHGVTLANKYPYTQTEMQCRQNETAGRPPR 238
            |.|||:|.||||...| |.||:||..:|.||: |::.|:.....|||...:.:|.||....:
plant   182 LISLSEQELVDCDTSY-NQGCNGGLMDYAFEFIIKNGGIDTEADYPYKAADGRCDQNRKNAK--- 242

  Fly   239 ESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTV 303
              :|.|..|..:....|..:|:.:|. .|::.::.|...:|:.||.|:: |..|.. ||:|.|..
plant   243 --VVTIDSYEDVPENSEASLKKALAH-QPISVAIEAGGRAFQLYSSGVF-DGLCGT-ELDHGVVA 302

  Fly   304 VGYGTENGRDYWIIKNSYSQNWGEGGFMRILRN---AGGFCGIASECSYPI 351
            ||||||||:||||::||:...|||.|::::.||   ..|.||||.|.||||
plant   303 VGYGTENGKDYWIVRNSWGNRWGESGYIKMARNIEAPTGKCGIAMEASYPI 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	18/84 (21%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	91/222 (41%)
RD21B	NP_568620.1	Inhibitor_I29	50..109	CDD:214853	13/62 (21%)
		Peptidase_C1	138..353	CDD:278538	93/224 (42%)
		GRAN	377..433	CDD:197621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780