Protein Alignment CG6347 and Ctsb

DIOPT Version :9

• Sequence 1: NP_610906.1
• Gene: CG6347 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_072119.2
• Gene: Ctsb / 64529
• RGDID: 621509
• Length: 339
• Species: Rattus norvegicus
• Alignment Length: 386
• Identity: 97/386 - (25%)
• Similarity: 146/386 - (37%)
• Gaps: 108/386 - (27%)

  Fly     7 MWLQMTLGLALLGAVSLQQLQSFPKLCDVQNFDDFLRQTGKVYSDEERVYRESIFAAKMSLITLS 71
            ||..:.....||...|.....||..|.     ||.:....|                       .
  Rat     1 MWWSLIPLSCLLALTSAHDKPSFHPLS-----DDMINYINK-----------------------Q 37

  Fly    72 NKNADNGVSGFRLGVNTLADMTRKEIATLLGS-KISE---FGERYTNGHINFVTARNPASANLPE 132
            |.....|.:.:.:.::.|    :|...|:||. |:.|   |.|                ..||||
  Rat    38 NTTWQAGRNFYNVDISYL----KKLCGTVLGGPKLPERVGFSE----------------DINLPE 82

  Fly   133 MFDWREKGGVTPP----GFQGVGCGACWSFATTGALEGHLFRRTG--VLASLSQQNLVDCADDYG 191
            .||.||:....|.    ..|| .||:||:|....|:...:...|.  |...:|.::|:.|.....
  Rat    83 SFDAREQWSNCPTIAQIRDQG-SCGSCWAFGAVEAMSDRICIHTNGRVNVEVSAEDLLTCCGIQC 146

  Fly   192 NMGCDGGFQEYGFEYIRDHGVTLANKY-------PYTQTEMQCRQNETAGRPP------------ 237
            ..||:||:....:.:....|:.....|       |||..  .|..:....|||
  Rat   147 GDGCNGGYPSGAWNFWTRKGLVSGGVYNSHIGCLPYTIP--PCEHHVNGSRPPCTGEGDTPKCNK 209

  Fly   238 ----------RESLVKIRDYATITPGDEEKMKEVIATL---GPLACSMNADTI--SFEQYSGGIY 287
                      :|.  |...|.:.:..|.|  ||::|.:   ||:.   .|.|:  .|..|..|:|
  Rat   210 MCEAGYSTSYKED--KHYGYTSYSVSDSE--KEIMAEIYKNGPVE---GAFTVFSDFLTYKSGVY 267

  Fly   288 EDEECNQGEL--NHSVTVVGYGTENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASE 346
            :.|   .|::  .|::.::|:|.|||..||::.||::.:||:.||.:|||.. ..|||.||
  Rat   268 KHE---AGDVMGGHAIRILGWGIENGVPYWLVANSWNVDWGDNGFFKILRGE-NHCGIESE 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	7/58 (12%)
		Peptidase_C1A	131..350	CDD:239068	73/258 (28%)
Ctsb	NP_072119.2	Propeptide_C1	26..65	CDD:285358	10/70 (14%)
		Peptidase_C1A_CathepsinB	81..328	CDD:239111	73/258 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820