Protein Alignment CtsL2 and ctsbb

DIOPT Version :10

• Sequence 1: NP_610906.1
• Gene: CtsL2 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_001418075.1
• Gene: ctsbb / 569298
• ZFINID: ZDB-GENE-070323-1
• Length: 326
• Species: Danio rerio
• Alignment Length: 342
• Identity: 87/342 - (25%)
• Similarity: 148/342 - (43%)
• Gaps: 74/342 - (21%)

  Fly    55 VYRESIFA------AKMSLIT----LSNKNADNGVSGFRLGVNTLADMTRKEIATLLGSKISEFG 109
            ::|..:||      |:..|.|    :|..||..  |.:..||| ..::.:|.:.:|.|:.:.  |
Zfish     1 MWRVCVFALLSVTCARPQLHTHDEMISFINAAR--STWTAGVN-FDNVPKKYLKSLCGTVLK--G 60

  Fly   110 ERYTNGHINFVTARNPASANLPEMFDWREK-------GGVTPPGFQGVGCGACWSFATTGALEGH 167
            .|..:      |.::..:..||:.||.|::       ..:...|    .||:||:|....::...
Zfish    61 PRLPH------TVKHSTNVKLPDSFDLRDQWPNCKTLNQIRDQG----SCGSCWAFGAVESISDR 115

  Fly   168 LFRRTGVLAS--LSQQNLVDCADDYGNMGCDGGFQEYGFEYIRDHGVTLANKY-------PYTQT 223
            :...:....|  :|.::|:.|.|..| .||.|||....::|.|..|:.....|       ||:..
Zfish   116 ICIHSKGKQSPEISAEDLLSCCDQCG-FGCSGGFPAEAWDYWRRSGLVTGGLYNSDVGCRPYSIA 179

  Fly   224 EMQCRQNETAGRP--------PRESLVKIRDYAT-------------ITPGDEEKMKEVIATLGP 267
              .|..:....||        |:.:.|.|..|:.             ..|.|::::...:.|.||
Zfish   180 --PCEHHVNGTRPPCSGEQDTPKCTGVCIPKYSVPYKQDKHFGSKVYNVPSDQQQIMTELYTNGP 242

  Fly   268 LACSMNADTI--SFEQYSGGIYEDEECNQGEL-NHSVTVVGYGTENGRDYWIIKNSYSQNWGEGG 329
            :..   |.|:  .|..|..|:|  :......| .|:|.::|:|.|||..:|::.||::.:||:.|
Zfish   243 VEA---AFTVYEDFPLYKSGVY--QHLTGSALGGHAVKILGWGEENGTPFWLVANSWNSDWGDNG 302

  Fly   330 FMRILRNAGGFCGIASE 346
            :.:|||.... |||.||
Zfish   303 YFKILRGHDE-CGIESE 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL2	NP_610906.1	Inhibitor_I29	38..97	CDD:462410	14/51 (27%)
		Peptidase_C1A	131..350	CDD:239068	67/256 (26%)
ctsbb	NP_001418075.1	Propeptide_C1	23..60	CDD:462365	10/41 (24%)
		Peptidase_C1A_CathepsinB	76..322	CDD:239111	67/256 (26%)