DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6347 and Ctsr

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_064680.1	Gene:	Ctsr / 56835	MGIID:	1861723	Length:	334	Species:	Mus musculus

Alignment Length:	320	Identity:	111/320 - (34%)
Similarity:	169/320 - (52%)	Gaps:	19/320 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 FDDFLRQTGKVYSDEERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLLG 102
            :.|:..:..|.||.:|...:..::..|:.:|.|.|:....|.:||.:.:|...|.|.:|...::
Mouse    29 WQDWKIKYNKSYSLKEEKLKRVVWEEKLKMIKLHNRENSLGKNGFTMKMNEFGDQTDEEFRKMM- 92

  Fly   103 SKISEFGERYTNGHINFVTARNPASANLPEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGH 167
            .:||.:..|....     ..:..|.:.||:..|||:||.|||...|| .|.|||:||.|||:|..
Mouse    93 IEISVWTHREGKS-----IMKREAGSILPKFVDWRKKGYVTPVRRQG-DCDACWAFAVTGAIEAQ 151

  Fly   168 LFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQEYGFEYI-RDHGVTLANKYPYTQTEMQCRQNE 231
            ...:||.|..||.||||||:...||.||.||.....|:|: .:.|:.....|||...:..||.|
Mouse   152 AIWQTGKLTPLSVQNLVDCSKPQGNNGCLGGDTYNAFQYVLHNGGLESEATYPYEGKDGPCRYN- 215

  Fly   232 TAGRPPRESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGE 296
                 |:.|..:|..:.:: |..|:.:...:||:||:...::|...||:.|.||||.:..|:...
Mouse   216 -----PKNSKAEITGFVSL-PQSEDILMAAVATIGPITAGIDASHESFKNYKGGIYHEPNCSSDT 274

  Fly   297 LNHSVTVVGYGTE----NGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYPIL 352
            :.|.|.|||||.:    :|..||:||||:.:.||..|:|::.::....|||||...||.:
Mouse   275 VTHGVLVVGYGFKGIETDGNHYWLIKNSWGKRWGIRGYMKLAKDKNNHCGIASYAHYPTI 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	15/58 (26%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	88/223 (39%)
Ctsr	NP_064680.1	PTZ00203	15..332	CDD:185513	109/316 (34%)
		Inhibitor_I29	29..87	CDD:214853	15/57 (26%)
		Peptidase_C1A	116..332	CDD:239068	88/223 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830