DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and cts12

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_021329137.1	Gene:	cts12 / 567046	ZFINID:	ZDB-GENE-050208-336	Length:	349	Species:	Danio rerio

Alignment Length:	309	Identity:	126/309 - (40%)
Similarity:	186/309 - (60%)	Gaps:	16/309 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 YSDE-ERVYRESIFAAKMSLITLSNKNADNGVSGFRLGVNTLADMTRKEIATLLGSKISEFGER- 111
            |.:| |.|:|::|:...|..|..:|.:...|:|.|::.:|...|:|..|...||||||...|.|
Zfish    52 YDEESEDVHRKTIWETNMQKIWKNNNDFSFGLSMFKMAMNKYGDLTSVEYKRLLGSKIKGTGNRK 116

  Fly   112 --YTNGHINFVTARNPASANLPEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGV 174
              .|:..:..:.|:.....|:    |:|.||.||....||. ||:||||:||||:||.:::.||.
Zfish   117 GKITSAQMLRLNAKRLGVTNI----DYRAKGYVTEVKDQGY-CGSCWSFSTTGAIEGQMYKHTGR 176

  Fly   175 LASLSQQNLVDCADDYGNMGCDGGFQEYGFEYIRDHGVTLANKYPYTQTEMQ-CRQNETAGRPPR 238
            |.|||:|.||||:..||..||.|.:....::|:.::.:..::.||||..:.| |...:..
Zfish   177 LVSLSEQQLVDCSRSYGTYGCSGAWMANAYDYVINNALESSDTYPYTSVDTQPCFYEKNL----- 236

  Fly   239 ESLVKIRDYATITPGDEEKMKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTV 303
             ::..|.||..:..|:|:.:.:.:||:||::.:::||..||..||.|||::..||...|||:|.|
Zfish   237 -AMAGISDYRFVPAGNEQALADAVATVGPVSVAIDADNPSFLFYSSGIYKESNCNPNNLNHAVLV 300

  Fly   304 VGYGTENGRDYWIIKNSYSQNWGEGGFMRILRNAGGFCGIASECSYPIL 352
            ||||:|.|.||||||||:...|||||:||::||....|||||...|||:
Zfish   301 VGYGSEEGTDYWIIKNSWGTGWGEGGYMRMIRNGKNTCGIASYALYPII 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	15/48 (31%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	96/219 (44%)
cts12	XP_021329137.1	Inhibitor_I29	41..101	CDD:311939	15/48 (31%)
cts12	XP_021329137.1	Peptidase_C1A	135..347	CDD:239068	97/222 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830