Protein Alignment CtsL2 and Cts7

DIOPT Version :10

• Sequence 1: NP_610906.1
• Gene: CtsL2 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_062412.1
• Gene: Cts7 / 56092
• MGIID: 1860262
• Length: 331
• Species: Mus musculus
• Alignment Length: 359
• Identity: 127/359 - (35%)
• Similarity: 190/359 - (52%)
• Gaps: 37/359 - (10%)

  Fly     3 MCSTMWLQ-MTLGLALLGAVSLQQLQSFPKLCDVQNFDDFLRQTGKVYSDEERVYRESIFAAKMS 66
            |..|::|. :.||:||........|.:        .::::.|...:.||.||...|.:::...:.
Mouse     1 MTPTVFLSILCLGVALAAPAPDYNLDA--------EWEEWKRSNDRTYSPEEEKQRRAVWEGNVK 57

  Fly    67 LITLSNKNADNG--VSGFRLGVNTLADMTRKEIATLLGSKISEFGERYTNG-HINFVTARNPASA 128
            .|  .....:||  ::.|.:.:|...|||.:|:..|..|  |.:..|  || ||.   .|||
Mouse    58 WI--KQHIMENGLWMNNFTIEMNEFGDMTGEEMKMLTES--SSYPLR--NGKHIQ---KRNP--- 110

  Fly   129 NLPEMFDWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNM 193
            .:|...|||::|.|||...|| .|||||:|:.|..:||.||::||.|..||.|||:||:..||..
Mouse   111 KIPPTLDWRKEGYVTPVRRQG-SCGACWAFSVTACIEGQLFKKTGKLIPLSVQNLMDCSVSYGTK 174

  Fly   194 GCDGGFQEYGFEYIRDHGVTLAN-KYPYTQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEK 257
            |||||.....|:|::::|...|. .|||......||..      |..|:||:..: .:.|.:||.
Mouse   175 GCDGGRPYDAFQYVKNNGGLEAEATYPYEAKAKHCRYR------PERSVVKVNRF-FVVPRNEEA 232

  Fly   258 MKEVIATLGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTVVGYGTE----NGRDYWIIK 318
            :.:.:.|.||:|.:::....||..|.||||.:.:|.:..|:|.:.:||||.|    ..|.||::|
Mouse   233 LLQALVTHGPIAVAIDGSHASFHSYRGGIYHEPKCRKDTLDHGLLLVGYGYEGHESENRKYWLLK 297

  Fly   319 NSYSQNWGEGGFMRILRNAGGFCGIASECSYPIL 352
            ||:.:.|||.|:|::.|....:|||||...||.|
Mouse   298 NSHGERWGENGYMKLPRGQNNYCGIASYAMYPAL 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsL2	NP_610906.1	Inhibitor_I29	38..97	CDD:462410	14/60 (23%)
		Peptidase_C1A	131..350	CDD:239068	90/223 (40%)
Cts7	NP_062412.1	Inhibitor_I29	29..87	CDD:214853	14/59 (24%)
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:18776147	33..50		6/16 (38%)
		Peptidase_C1A	113..329	CDD:239068	90/223 (40%)