DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and CG4847

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_725686.1	Gene:	CG4847 / 36973	FlyBaseID:	FBgn0034229	Length:	420	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	159/353 - (45%)
Similarity:	219/353 - (62%)	Gaps:	23/353 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LQMTLGLALLGAVS--LQQLQSFPKLCDVQNFDDFLRQTGKVY-SDEERVYRESIFAAKMSLITL 70
            ||...| |:..||.  .:.:...|.|.:||:|.|||.|:||.| |..:|...|..||:..:|:..
  Fly    82 LQNVAG-AVQNAVGNIAKAVPKVPLLSNVQDFGDFLSQSGKTYLSAADRALHEGAFASTKNLVEA 145

  Fly    71 SNKNADNGVSGFRLGVNTLADMTRKE-IATLLGSKISEFGERYTNGHINFVTARNPASANLPEMF 134
            .|.....||..|:..||..||:|..| ::.|.|.|.|...:......:..|   |..:..:|:.|
  Fly   146 GNAAFAQGVHTFKQAVNAFADLTHSEFLSQLTGLKRSPEAKARAAASLKLV---NLPAKPIPDAF 207

  Fly   135 DWREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDC--ADDYGNMGCDG 197
            ||||.|||||..|||. ||:||:||||||:|||.||:||.|.:||:||||||  .:|:|..||||
  Fly   208 DWREHGGVTPVKFQGT-CGSCWAFATTGAIEGHTFRKTGSLPNLSEQNLVDCGPVEDFGLNGCDG 271

  Fly   198 GFQEYGFEYIRD--HGVTLANKYPYTQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEKMKE 260
            ||||..|.:|.:  .||:....|||...:..|:.:.:      :|...::.:|.|.|.|||::|:
  Fly   272 GFQEAAFCFIDEVQKGVSQEGAYPYIDNKGTCKYDGS------KSGATLQGFAAIPPKDEEQLKK 330

  Fly   261 VIATLGPLACSMNA-DTISFEQYSGGIYEDEECNQGELNHSVTVVGYGTENGRDYWIIKNSYSQN 324
            |:|||||:|||:|. :|:  :.|:||||.|:|||:||.|||:.|||||:|.|:||||:|||:...
  Fly   331 VVATLGPVACSVNGLETL--KNYAGGIYNDDECNKGEPNHSILVVGYGSEKGQDYWIVKNSWDDT 393

  Fly   325 WGEGGFMRILRNAGGFCGIASECSYPIL 352
            |||.|:.|:.|.. .:|.||.|||||::
  Fly   394 WGEKGYFRLPRGK-NYCFIAEECSYPVV 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	24/60 (40%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	117/223 (52%)
CG4847	NP_725686.1	Inhibitor_I29	112..172	CDD:285458	23/59 (39%)
CG4847	NP_725686.1	Peptidase_C1A	204..418	CDD:239068	117/223 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452942
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	1	1.000	-	-		FOG0019589
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12411
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850