DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6347 and ctsla

DIOPT Version :9

Sequence 1:	NP_610906.1	Gene:	CG6347 / 36531	FlyBaseID:	FBgn0033874	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_005165325.1	Gene:	ctsla / 321453	ZFINID:	ZDB-GENE-030131-106	Length:	363	Species:	Danio rerio

Alignment Length:	349	Identity:	129/349 - (36%)
Similarity:	195/349 - (55%)	Gaps:	37/349 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ALLGAVSL-QQLQSFPKLCDVQNFDDFLRQTGKVYSDEERVYRESIFAAKMSLITLSNKNADNGV 79
            |:..|.:| |||.        .::|.:.:...|.|...|..:|..|:...:..|.:.|.....|:
Zfish    40 AVFAAPTLDQQLN--------DHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGI 96

  Fly    80 SGFRLGVNTLADMTRKEIATLL-GSKISEFGERYTNGHI----NFVTARNPASANLPEMFDWREK 139
            ..:|||:|...|||.:|...:: |.|..:  :|...|.:    ||:        .:|...|||||
Zfish    97 HTYRLGMNHFGDMTHEEFRQVMNGFKHKK--DRRFRGSLFMEPNFI--------EVPNKLDWREK 151

  Fly   140 GGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQEYGF 204
            |.|||...|| .||:||:|:|||||||.:||:||.|.|||:||||||:...||.||:||..:..|
Zfish   152 GYVTPVKDQG-ECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAF 215

  Fly   205 EYIRD-HGVTLANKYPYTQTEMQ-CRQNETAGRPPRESLVKIRDYATITPGDEEKMKEVIATLGP 267
            :|::| :|:.....|||..|:.| |..:      |:.|......:..|..|.|..:.:.||.:||
Zfish   216 QYVKDQNGLDSEESYPYLGTDDQPCHFD------PKNSAANDTGFVDIPSGKERALMKAIAAVGP 274

  Fly   268 LACSMNADTISFEQYSGGIYEDEECNQGELNHSVTVVGYGTE----NGRDYWIIKNSYSQNWGEG 328
            ::.:::|...||:.|..|||.::||:..||:|.|..||||.|    :|:.|||:|||:|:|||:.
Zfish   275 VSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDK 339

  Fly   329 GFMRILRNAGGFCGIASECSYPIL 352
            |::.:.::....||||:..|||::
Zfish   340 GYIYMAKDRHNHCGIATAASYPLV 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	16/58 (28%)
CG6347	NP_610906.1	Peptidase_C1A	131..350	CDD:239068	98/224 (44%)
ctsla	XP_005165325.1	Inhibitor_I29	55..113	CDD:214853	16/57 (28%)
ctsla	XP_005165325.1	Peptidase_C1	142..362	CDD:278538	99/226 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.930